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Emerging directions in tauopathy research

Buée, Luc ; Wildsmith, Kristin R. ; Alladi, Suvarna ; Bertucci, Taylor ; Boche, Delphine ; Bowles, Kathryn R. ; Boxer, Adam ; Brummet, Jennifer ; DeVos, Sarah L. and Diaz, Kristophe , et al. (2026) In Alzheimer's and Dementia 22(6).
Abstract

The Tau Global Conference 2025, hosted by the Alzheimer's Association, CurePSP, and the Rainwater Charitable Foundation, convened international experts from academia, industry, government, and philanthropy to explore advances and challenges in tauopathy research. The meeting highlighted progress across tau biology, including emerging models of tau regulation, degradation, and propagation; advances in biomarker development for the diagnosis and staging of tauopathies; and evolving therapeutic strategies targeting diverse aspects of tau pathophysiology. Discussions also emphasized the importance of cross-sector collaboration, and global initiatives to address disparities in tau research. This report synthesizes key insights from the... (More)

The Tau Global Conference 2025, hosted by the Alzheimer's Association, CurePSP, and the Rainwater Charitable Foundation, convened international experts from academia, industry, government, and philanthropy to explore advances and challenges in tauopathy research. The meeting highlighted progress across tau biology, including emerging models of tau regulation, degradation, and propagation; advances in biomarker development for the diagnosis and staging of tauopathies; and evolving therapeutic strategies targeting diverse aspects of tau pathophysiology. Discussions also emphasized the importance of cross-sector collaboration, and global initiatives to address disparities in tau research. This report synthesizes key insights from the conference and underscores the critical role of interdisciplinary, biomarker-driven, and globally inclusive approaches in accelerating the translation of tau research into effective clinical applications.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
biomarkers, neurodegeneration, precision medicine, tauopathies, therapeutics
in
Alzheimer's and Dementia
volume
22
issue
6
article number
e71431
publisher
Wiley
external identifiers
  • pmid:42324487
  • scopus:105042432798
ISSN
1552-5260
DOI
10.1002/alz.71431
language
English
LU publication?
yes
id
87dc91b5-5f89-41e5-9108-b5ae6f80d97c
date added to LUP
2026-07-03 12:01:34
date last changed
2026-08-28 17:05:41
@article{87dc91b5-5f89-41e5-9108-b5ae6f80d97c,
  abstract     = {{<p>The Tau Global Conference 2025, hosted by the Alzheimer's Association, CurePSP, and the Rainwater Charitable Foundation, convened international experts from academia, industry, government, and philanthropy to explore advances and challenges in tauopathy research. The meeting highlighted progress across tau biology, including emerging models of tau regulation, degradation, and propagation; advances in biomarker development for the diagnosis and staging of tauopathies; and evolving therapeutic strategies targeting diverse aspects of tau pathophysiology. Discussions also emphasized the importance of cross-sector collaboration, and global initiatives to address disparities in tau research. This report synthesizes key insights from the conference and underscores the critical role of interdisciplinary, biomarker-driven, and globally inclusive approaches in accelerating the translation of tau research into effective clinical applications.</p>}},
  author       = {{Buée, Luc and Wildsmith, Kristin R. and Alladi, Suvarna and Bertucci, Taylor and Boche, Delphine and Bowles, Kathryn R. and Boxer, Adam and Brummet, Jennifer and DeVos, Sarah L. and Diaz, Kristophe and Dreyer, Anna Jane and Duff, Karen and Duran-Aniotz, Claudia and Durrant, Claire S. and Farrell, Kurt and Fontana, Igor C. and Franzmeier, Nicolai and Frost, Bess and Horie, Kanta and Kaňovský, Petr and Kao, Aimee W. and Mahinrad, Simin and Malpetti, Maura and Morris, Huw R. and Palleis, Carla and Petrucelli, Leonard and Rexach, Jessica and Reyderman, Larisa and Rommel, Amy and Rowe, James B. and Sanabria Bohórquez, Sandra M. and Sato, Chihiro and Schöll, Michael and Schneider, Anja and de Silva, Rohan and Snyder, Heather M. and VandeVrede, Lawren and Varga, Andrew W. and Vogel, Jacob W. and Yeh, Felix L. and Yoo, Andrew S. and Carrillo, Maria C.}},
  issn         = {{1552-5260}},
  keywords     = {{biomarkers; neurodegeneration; precision medicine; tauopathies; therapeutics}},
  language     = {{eng}},
  number       = {{6}},
  publisher    = {{Wiley}},
  series       = {{Alzheimer's and Dementia}},
  title        = {{Emerging directions in tauopathy research}},
  url          = {{http://dx.doi.org/10.1002/alz.71431}},
  doi          = {{10.1002/alz.71431}},
  volume       = {{22}},
  year         = {{2026}},
}