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Low Free Testosterone is Associated with Hypogonadal Signs and Symptoms in Men with Normal Total Testosterone.

Antonio, Leen; Wu, Frederick C W; O'Neill, Terence W; Pye, Stephen R; Ahern, Tomas B; Laurent, Michaël R; Huhtaniemi, Ilpo T; Lean, Michael E J; Keevil, Brian G and Rastrelli, Giulia, et al. (2016) In The Journal of clinical endocrinology and metabolism 101(7). p.2647-2657
Abstract
During ageing, total testosterone (TT) declines and SHBG increases, resulting in a greater decrease in calculated free testosterone (cFT). Currently, guidelines suggest using TT to diagnose androgen deficiency and to reserve cFT only for men with borderline TT.
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Contribution to journal
publication status
published
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in
The Journal of clinical endocrinology and metabolism
volume
101
issue
7
pages
2647 - 2657
publisher
The Endocrine Society
external identifiers
  • PMID:26909800
  • Scopus:84978079951
  • WOS:000380224800006
ISSN
1945-7197
DOI
10.1210/jc.2015-4106
language
English
LU publication?
yes
id
2a22ff4e-3b72-4c2d-9e97-8cb33efa637d (old id 8821806)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26909800?dopt=Abstract
date added to LUP
2016-03-03 12:50:52
date last changed
2017-01-01 07:45:18
@article{2a22ff4e-3b72-4c2d-9e97-8cb33efa637d,
  abstract     = {During ageing, total testosterone (TT) declines and SHBG increases, resulting in a greater decrease in calculated free testosterone (cFT). Currently, guidelines suggest using TT to diagnose androgen deficiency and to reserve cFT only for men with borderline TT.},
  author       = {Antonio, Leen and Wu, Frederick C W and O'Neill, Terence W and Pye, Stephen R and Ahern, Tomas B and Laurent, Michaël R and Huhtaniemi, Ilpo T and Lean, Michael E J and Keevil, Brian G and Rastrelli, Giulia and Forti, Gianni and Bartfai, György and Casanueva, Felipe F and Kula, Krzysztof and Punab, Margus and Giwercman, Aleksander and Claessens, Frank and Decallonne, Brigitte and Vanderschueren, Dirk},
  issn         = {1945-7197},
  language     = {eng},
  number       = {7},
  pages        = {2647--2657},
  publisher    = {The Endocrine Society},
  series       = {The Journal of clinical endocrinology and metabolism},
  title        = {Low Free Testosterone is Associated with Hypogonadal Signs and Symptoms in Men with Normal Total Testosterone.},
  url          = {http://dx.doi.org/10.1210/jc.2015-4106},
  volume       = {101},
  year         = {2016},
}