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Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1 and 3 in Gastric and Esophageal Adenocarcinoma.

Hedner, Charlotta LU ; Borg, David LU ; Nodin, Björn LU ; Karnevi, Emelie LU ; Jirström, Karin LU and Eberhard, Jakob LU (2016) In PLoS ONE 11(2).
Abstract
Gastric and esophageal adenocarcinomas are major global cancer burdens. These cancer forms are characterized by a poor prognosis and a modest response to chemo- radio- and targeted treatment. Hence there is an obvious need for further enhanced diagnostic and treatment strategies. The aim of this study was to examine the expression and prognostic impact of human epidermal growth factor receptor 1 (HER1/EGFR) and 3 (HER3), as well as the occurrence of EGFR and KRAS mutations in gastric and esophageal adenocarcinoma.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
11
issue
2
publisher
Public Library of Science
external identifiers
  • pmid:26844548
  • scopus:84959018090
  • wos:000369552800029
ISSN
1932-6203
DOI
10.1371/journal.pone.0148101
language
English
LU publication?
yes
id
a69dc566-dbb0-4981-844c-04f1d745919e (old id 8829316)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26844548?dopt=Abstract
date added to LUP
2016-03-01 13:50:34
date last changed
2017-08-06 03:53:06
@article{a69dc566-dbb0-4981-844c-04f1d745919e,
  abstract     = {Gastric and esophageal adenocarcinomas are major global cancer burdens. These cancer forms are characterized by a poor prognosis and a modest response to chemo- radio- and targeted treatment. Hence there is an obvious need for further enhanced diagnostic and treatment strategies. The aim of this study was to examine the expression and prognostic impact of human epidermal growth factor receptor 1 (HER1/EGFR) and 3 (HER3), as well as the occurrence of EGFR and KRAS mutations in gastric and esophageal adenocarcinoma.},
  articleno    = {e0148101},
  author       = {Hedner, Charlotta and Borg, David and Nodin, Björn and Karnevi, Emelie and Jirström, Karin and Eberhard, Jakob},
  issn         = {1932-6203},
  language     = {eng},
  number       = {2},
  publisher    = {Public Library of Science},
  series       = {PLoS ONE},
  title        = {Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1 and 3 in Gastric and Esophageal Adenocarcinoma.},
  url          = {http://dx.doi.org/10.1371/journal.pone.0148101},
  volume       = {11},
  year         = {2016},
}