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Study protocol of SWEPIS a Swedish multicentre register based randomised controlled trial to compare induction of labour at 41 completed gestational weeks versus expectant management and induction at 42 completed gestational weeks.

Elden, Helen; Hagberg, Henrik; Wessberg, Anna; Sengpiel, Verena; Herbst, Andreas LU ; Bullarbo, Maria; Bergh, Christina; Bolin, Kristian; Malbasic, Snezana and Saltvedt, Sissel, et al. (2016) In BMC Pregnancy and Childbirth 16(1).
Abstract
Observational data shows that postterm pregnancy (≥42 gestational weeks, GW) and late term pregnancy (≥41 GW), as compared to term pregnancy, is associated with an increased risk for adverse outcome for the mother and infant. Standard care in many countries is induction of labour at 42 GW. There is insufficient scientific support that induction of labour at 41 GW, as compared with expectant management and induction at 42 GW will reduce perinatal mortality and morbidity without an increase in operative deliveries, negative delivery experiences or higher costs. Large randomised studies are needed since important outcomes; such as perinatal mortality and hypoxic ischaemic encephalopathy are rare events.
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type
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published
subject
in
BMC Pregnancy and Childbirth
volume
16
issue
1
publisher
BioMed Central
external identifiers
  • pmid:26951777
  • scopus:84980335279
  • wos:000371575400001
ISSN
1471-2393
DOI
10.1186/s12884-016-0836-9
language
English
LU publication?
no
id
274fa27b-f4cc-4852-a035-f955192e0622 (old id 8853097)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26951777?dopt=Abstract
date added to LUP
2016-03-16 11:41:46
date last changed
2017-08-27 04:57:52
@article{274fa27b-f4cc-4852-a035-f955192e0622,
  abstract     = {Observational data shows that postterm pregnancy (≥42 gestational weeks, GW) and late term pregnancy (≥41 GW), as compared to term pregnancy, is associated with an increased risk for adverse outcome for the mother and infant. Standard care in many countries is induction of labour at 42 GW. There is insufficient scientific support that induction of labour at 41 GW, as compared with expectant management and induction at 42 GW will reduce perinatal mortality and morbidity without an increase in operative deliveries, negative delivery experiences or higher costs. Large randomised studies are needed since important outcomes; such as perinatal mortality and hypoxic ischaemic encephalopathy are rare events.},
  articleno    = {49},
  author       = {Elden, Helen and Hagberg, Henrik and Wessberg, Anna and Sengpiel, Verena and Herbst, Andreas and Bullarbo, Maria and Bergh, Christina and Bolin, Kristian and Malbasic, Snezana and Saltvedt, Sissel and Stephansson, Olof and Wikström, Anna-Karin and Ladfors, Lars and Wennerholm, Ulla-Britt},
  issn         = {1471-2393},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {BMC Pregnancy and Childbirth},
  title        = {Study protocol of SWEPIS a Swedish multicentre register based randomised controlled trial to compare induction of labour at 41 completed gestational weeks versus expectant management and induction at 42 completed gestational weeks.},
  url          = {http://dx.doi.org/10.1186/s12884-016-0836-9},
  volume       = {16},
  year         = {2016},
}