Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Gas in Scattering Media Absorption Spectroscopy on Small and Large Scales: Towards the Extension of Lung Spectroscopic Monitoring to Adults

Sahlberg, Anna-Lena LU ; Lin, Yueyu ; Lundin, Patrik LU ; Krite Svanberg, Emilie LU ; Svanberg, Katarina LU and Svanberg, Sune LU (2021) In Translational Biophotonics
Abstract
Numerous natural materials are porous, contain free gas, and are scattering light strongly. Scattering brings about a strong trapping of light and an associated prolonged transit time for photons through a medium. In contrast to the matrix materials, gas enclosures require very narrow‐band laser radiation for probing. We have in the present study used the gas in scattering media absorption spectroscopy (GASMAS) method to study free oxygen in thin (cm) samples utilizing a tunable diode laser, while a pulsed dye laser was employed in corresponding measurements on larger samples, up to the meter scale. Time‐resolved spectroscopy was in both cases used to assess the temporal distribution of the detected photons, mapping the path lengths... (More)
Numerous natural materials are porous, contain free gas, and are scattering light strongly. Scattering brings about a strong trapping of light and an associated prolonged transit time for photons through a medium. In contrast to the matrix materials, gas enclosures require very narrow‐band laser radiation for probing. We have in the present study used the gas in scattering media absorption spectroscopy (GASMAS) method to study free oxygen in thin (cm) samples utilizing a tunable diode laser, while a pulsed dye laser was employed in corresponding measurements on larger samples, up to the meter scale. Time‐resolved spectroscopy was in both cases used to assess the temporal distribution of the detected photons, mapping the path lengths through the media, which ranged between few centimeters up to 100 m. This study explores the feasibility to extend recent successful monitoring of gases in neonatal infant lungs to the case of larger children or even adults, which could have very important applications, for example, in ventilator setting optimization for severely ill patients, suffering, for example, from SARS‐CoV‐2. The conclusion of our work is that this goal most realistically can be reached by applying intra‐tracheal laser light illumination at the 1 W power level, employing a tapered amplifier, injected with a distributed feed‐back diode‐laser oscillator output and combined with wavelength‐modulation spectroscopy. (Less)
Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Translational Biophotonics
publisher
Wiley
ISSN
2627-1850
DOI
10.1002/tbio.202100003
language
English
LU publication?
yes
id
890e1dfd-5230-4919-ba1c-17b37bf403af
date added to LUP
2022-03-31 10:21:30
date last changed
2022-04-03 11:34:04
@article{890e1dfd-5230-4919-ba1c-17b37bf403af,
  abstract     = {{Numerous natural materials are porous, contain free gas, and are scattering light strongly. Scattering brings about a strong trapping of light and an associated prolonged transit time for photons through a medium. In contrast to the matrix materials, gas enclosures require very narrow‐band laser radiation for probing. We have in the present study used the gas in scattering media absorption spectroscopy (GASMAS) method to study free oxygen in thin (cm) samples utilizing a tunable diode laser, while a pulsed dye laser was employed in corresponding measurements on larger samples, up to the meter scale. Time‐resolved spectroscopy was in both cases used to assess the temporal distribution of the detected photons, mapping the path lengths through the media, which ranged between few centimeters up to 100 m. This study explores the feasibility to extend recent successful monitoring of gases in neonatal infant lungs to the case of larger children or even adults, which could have very important applications, for example, in ventilator setting optimization for severely ill patients, suffering, for example, from SARS‐CoV‐2. The conclusion of our work is that this goal most realistically can be reached by applying intra‐tracheal laser light illumination at the 1 W power level, employing a tapered amplifier, injected with a distributed feed‐back diode‐laser oscillator output and combined with wavelength‐modulation spectroscopy.}},
  author       = {{Sahlberg, Anna-Lena and Lin, Yueyu and Lundin, Patrik and Krite Svanberg, Emilie and Svanberg, Katarina and Svanberg, Sune}},
  issn         = {{2627-1850}},
  language     = {{eng}},
  publisher    = {{Wiley}},
  series       = {{Translational Biophotonics}},
  title        = {{Gas in Scattering Media Absorption Spectroscopy on Small and Large Scales: Towards the Extension of Lung Spectroscopic Monitoring to Adults}},
  url          = {{http://dx.doi.org/10.1002/tbio.202100003}},
  doi          = {{10.1002/tbio.202100003}},
  year         = {{2021}},
}