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Pilocarpine treatment of xerostomia in head and neck patients

Leek, Håkan LU and Albertsson, Maria LU (2002) In Micron 33(2). p.153-155
Abstract
We studied the effect of pilocarpine hydrochloride, a parasympathicomimewtic agent, on major salivary gland output and subjective responses in 40 patients with salivary hypofunction. Pilocarpine increased salivary output or gave significant symptomatic relief in 21 of the 40 patients. The women fared better than the men. Side effects were uncommon, were generally mild, and caused no treatment interruption. These results indicate that pilocarpine is effective in relieving the signs and symptoms of postradiation xerostomia. (C) 2001 Elsevier Science Ltd. All rights reserved.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
head and neck carcinoma, pilocarpine, xerostomia
in
Micron
volume
33
issue
2
pages
153 - 155
publisher
Elsevier
external identifiers
  • wos:000171809500007
  • pmid:11567884
  • scopus:0036027773
ISSN
1878-4291
DOI
10.1016/S0968-4328(01)00004-X
language
English
LU publication?
yes
id
f1c5df94-ea51-42c4-a551-f4b9852c2e2c (old id 893826)
date added to LUP
2008-01-23 13:16:02
date last changed
2017-01-01 04:20:46
@article{f1c5df94-ea51-42c4-a551-f4b9852c2e2c,
  abstract     = {We studied the effect of pilocarpine hydrochloride, a parasympathicomimewtic agent, on major salivary gland output and subjective responses in 40 patients with salivary hypofunction. Pilocarpine increased salivary output or gave significant symptomatic relief in 21 of the 40 patients. The women fared better than the men. Side effects were uncommon, were generally mild, and caused no treatment interruption. These results indicate that pilocarpine is effective in relieving the signs and symptoms of postradiation xerostomia. (C) 2001 Elsevier Science Ltd. All rights reserved.},
  author       = {Leek, Håkan and Albertsson, Maria},
  issn         = {1878-4291},
  keyword      = {head and neck carcinoma,pilocarpine,xerostomia},
  language     = {eng},
  number       = {2},
  pages        = {153--155},
  publisher    = {Elsevier},
  series       = {Micron},
  title        = {Pilocarpine treatment of xerostomia in head and neck patients},
  url          = {http://dx.doi.org/10.1016/S0968-4328(01)00004-X},
  volume       = {33},
  year         = {2002},
}