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Evaluation of endometrial receptivity during in-vitro fertilization using three-dimensional power Doppler ultrasound

Jarvela, IY; Sladkevicius, Povilas LU ; Kelly, S; Ojha, K; Campbell, S and Nargund, G (2005) In Ultrasound in Obstetrics & Gynecology 26(7). p.765-769
Abstract
Objective To compare sonographic endometrial characteristics in in-vitro fertilization (IVF) cycles between women who conceive and those who do not. Methods Thirty-five women undergoing IVF treatment participated in the study. Using three-dimensional (3D) power Doppler ultrasound, we assessed endometrial patterns, volume and vascularization, after follicle stimulating hormone (FSH) stimulation but before human chorionic gonadotropin (bCG) administration (referred to hereafter as 'after FSH stimulation) and again on the day of oocyte retrieval. Results The pregnancy rate was 37% (13/35). After FSH stimulation, 29 of the 35 women bad a triple-line endometrial pattern, compared with five out of 35 on the day of oocyte retrieval. in those who... (More)
Objective To compare sonographic endometrial characteristics in in-vitro fertilization (IVF) cycles between women who conceive and those who do not. Methods Thirty-five women undergoing IVF treatment participated in the study. Using three-dimensional (3D) power Doppler ultrasound, we assessed endometrial patterns, volume and vascularization, after follicle stimulating hormone (FSH) stimulation but before human chorionic gonadotropin (bCG) administration (referred to hereafter as 'after FSH stimulation) and again on the day of oocyte retrieval. Results The pregnancy rate was 37% (13/35). After FSH stimulation, 29 of the 35 women bad a triple-line endometrial pattern, compared with five out of 35 on the day of oocyte retrieval. in those who bad a triple-line pattern after FSH stimulation the pregnancy rate was 44.8% (13/29) and it was 0% (016) in those with a homogeneous pattern (chi-square test, P = 0.039). If a triple-line pattern was present on the day of oocyte retrieval the pregnancy rate was 80.0% (415), whereas if the pattern was homogeneous the pregnancy rate was 30.0% (9/30) (P = 0.032). There were no differences between those who conceived and those who did not in endometrial thickness, volume or vascularization on either day examined. Endometrial volume decreased significantly after bCG injection in women who conceived, but not in those who did not conceive. In both groups endometrial and subendometrial vascularization decreased after bCG injection, while the endometrial thickness remained unchanged. Conclusions The existence of a homogeneous endometrial pattern after FSH stimulation seems to be a prognostic sign of an adverse outcome in IVF, while a triple-line pattern after FSH stimulation and a decrease in endometrial volume appear to be associated with conception. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
subendometrial flow, vascularization index, triple line
in
Ultrasound in Obstetrics & Gynecology
volume
26
issue
7
pages
765 - 769
publisher
John Wiley & Sons
external identifiers
  • pmid:16270378
  • wos:000234027800014
  • scopus:29144432276
ISSN
1469-0705
DOI
10.1002/uog.2628
language
English
LU publication?
yes
id
ba22ddae-629d-4183-b4c6-ac639047cf14 (old id 894279)
date added to LUP
2008-01-16 11:40:27
date last changed
2017-10-29 04:09:06
@article{ba22ddae-629d-4183-b4c6-ac639047cf14,
  abstract     = {Objective To compare sonographic endometrial characteristics in in-vitro fertilization (IVF) cycles between women who conceive and those who do not. Methods Thirty-five women undergoing IVF treatment participated in the study. Using three-dimensional (3D) power Doppler ultrasound, we assessed endometrial patterns, volume and vascularization, after follicle stimulating hormone (FSH) stimulation but before human chorionic gonadotropin (bCG) administration (referred to hereafter as 'after FSH stimulation) and again on the day of oocyte retrieval. Results The pregnancy rate was 37% (13/35). After FSH stimulation, 29 of the 35 women bad a triple-line endometrial pattern, compared with five out of 35 on the day of oocyte retrieval. in those who bad a triple-line pattern after FSH stimulation the pregnancy rate was 44.8% (13/29) and it was 0% (016) in those with a homogeneous pattern (chi-square test, P = 0.039). If a triple-line pattern was present on the day of oocyte retrieval the pregnancy rate was 80.0% (415), whereas if the pattern was homogeneous the pregnancy rate was 30.0% (9/30) (P = 0.032). There were no differences between those who conceived and those who did not in endometrial thickness, volume or vascularization on either day examined. Endometrial volume decreased significantly after bCG injection in women who conceived, but not in those who did not conceive. In both groups endometrial and subendometrial vascularization decreased after bCG injection, while the endometrial thickness remained unchanged. Conclusions The existence of a homogeneous endometrial pattern after FSH stimulation seems to be a prognostic sign of an adverse outcome in IVF, while a triple-line pattern after FSH stimulation and a decrease in endometrial volume appear to be associated with conception.},
  author       = {Jarvela, IY and Sladkevicius, Povilas and Kelly, S and Ojha, K and Campbell, S and Nargund, G},
  issn         = {1469-0705},
  keyword      = {subendometrial flow,vascularization index,triple line},
  language     = {eng},
  number       = {7},
  pages        = {765--769},
  publisher    = {John Wiley & Sons},
  series       = {Ultrasound in Obstetrics & Gynecology},
  title        = {Evaluation of endometrial receptivity during in-vitro fertilization using three-dimensional power Doppler ultrasound},
  url          = {http://dx.doi.org/10.1002/uog.2628},
  volume       = {26},
  year         = {2005},
}