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Results of second-look resection after primary resection of T1 tumour of the urinary bladder

Jahnson, S; Wiklund, F; Duchek, M; Mestad, O; Rintala, E; Hellsten, Sverker LU and Malmstrom, PU (2005) In Scandinavian Journal of Urology and Nephrology1967-01-01+01:002013-01-01+01:00 39(3). p.206-210
Abstract
Objective. To study residual tumours at second-look resection in patients resected 4-8 weeks earlier for T1 tumours of the urinary bladder. Material and methods. All patients randomized in the ongoing Nordic T1G2-G3 Bladder Sparing Study with monitored data available were included in the study. Data on residual tumours at second-look resection were compared to basic patient and tumour characteristics. Results. There were 72 patients (56%) without and 57 with residual exophytic tumours. In the former group, 20 patients (28%) had carcinoma in situ, compared to 19 (33%) in the latter group. Potentially dangerous tumours (either carcinoma in situ, T1 or Ta grade 3) were observed in 55 patients (43%). Multiple tumours at primary resection were... (More)
Objective. To study residual tumours at second-look resection in patients resected 4-8 weeks earlier for T1 tumours of the urinary bladder. Material and methods. All patients randomized in the ongoing Nordic T1G2-G3 Bladder Sparing Study with monitored data available were included in the study. Data on residual tumours at second-look resection were compared to basic patient and tumour characteristics. Results. There were 72 patients (56%) without and 57 with residual exophytic tumours. In the former group, 20 patients (28%) had carcinoma in situ, compared to 19 (33%) in the latter group. Potentially dangerous tumours (either carcinoma in situ, T1 or Ta grade 3) were observed in 55 patients (43%). Multiple tumours at primary resection were more prone to residual tumour at second-look resection than single tumours. No other tumour or patient characteristics could predict the occurrence of a residual tumour. Conclusions. Residual tumours are frequently observed at second-look resection 4-8 weeks after primary resection of T1 tumours. The majority of residual tumours detected at this stage are potentially dangerous; therefore, early second-look resection followed by intravesical instillation therapy is mandatory in patients with T1 tumours of the urinary bladder. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
bladder cancer, primary resection, second-look resection
in
Scandinavian Journal of Urology and Nephrology1967-01-01+01:002013-01-01+01:00
volume
39
issue
3
pages
206 - 210
publisher
Taylor & Francis
external identifiers
  • wos:000230486700004
  • pmid:16127800
  • scopus:22144450372
ISSN
0036-5599
DOI
10.1080/00365590510007793
language
English
LU publication?
yes
id
2cba81cd-188e-402f-9104-c3d7d90ae4b1 (old id 895030)
date added to LUP
2008-01-16 11:30:19
date last changed
2017-08-06 04:31:24
@article{2cba81cd-188e-402f-9104-c3d7d90ae4b1,
  abstract     = {Objective. To study residual tumours at second-look resection in patients resected 4-8 weeks earlier for T1 tumours of the urinary bladder. Material and methods. All patients randomized in the ongoing Nordic T1G2-G3 Bladder Sparing Study with monitored data available were included in the study. Data on residual tumours at second-look resection were compared to basic patient and tumour characteristics. Results. There were 72 patients (56%) without and 57 with residual exophytic tumours. In the former group, 20 patients (28%) had carcinoma in situ, compared to 19 (33%) in the latter group. Potentially dangerous tumours (either carcinoma in situ, T1 or Ta grade 3) were observed in 55 patients (43%). Multiple tumours at primary resection were more prone to residual tumour at second-look resection than single tumours. No other tumour or patient characteristics could predict the occurrence of a residual tumour. Conclusions. Residual tumours are frequently observed at second-look resection 4-8 weeks after primary resection of T1 tumours. The majority of residual tumours detected at this stage are potentially dangerous; therefore, early second-look resection followed by intravesical instillation therapy is mandatory in patients with T1 tumours of the urinary bladder.},
  author       = {Jahnson, S and Wiklund, F and Duchek, M and Mestad, O and Rintala, E and Hellsten, Sverker and Malmstrom, PU},
  issn         = {0036-5599},
  keyword      = {bladder cancer,primary resection,second-look resection},
  language     = {eng},
  number       = {3},
  pages        = {206--210},
  publisher    = {Taylor & Francis},
  series       = {Scandinavian Journal of Urology and Nephrology1967-01-01+01:002013-01-01+01:00},
  title        = {Results of second-look resection after primary resection of T1 tumour of the urinary bladder},
  url          = {http://dx.doi.org/10.1080/00365590510007793},
  volume       = {39},
  year         = {2005},
}