Hyperprolactinemia in some Meniere patients even in the absence of incapacitating vertigo
(2005) In Hearing Research 203(1-2). p.154-158- Abstract
- Stress can be a significant factor influencing ear pathologies and is often reported to trigger the symptoms of Meniere's disease. Both physiological and psychological stress provokes the release of prolactin from the pituitary thus allowing the classification of prolactin as a major stress hormone. We investigated the level of the stress hormone prolactin in a Swedish population with early symptoms of Meniere's disease. The median prolactin level in the Meniere patients (n = 33) was not significantly different from that of non-Meniere patients (n = 23). However, in the Meniere group one female (90 year old) had prolactin levels in the upper normal range for women, one male (77 year old) had prolactin levels above the normal limit for men,... (More)
- Stress can be a significant factor influencing ear pathologies and is often reported to trigger the symptoms of Meniere's disease. Both physiological and psychological stress provokes the release of prolactin from the pituitary thus allowing the classification of prolactin as a major stress hormone. We investigated the level of the stress hormone prolactin in a Swedish population with early symptoms of Meniere's disease. The median prolactin level in the Meniere patients (n = 33) was not significantly different from that of non-Meniere patients (n = 23). However, in the Meniere group one female (90 year old) had prolactin levels in the upper normal range for women, one male (77 year old) had prolactin levels above the normal limit for men, and a third patient (76 year old female) presented hyper prolactinemia with more than twice the normal level. MR1 confirmed a pituitary adenoma in this patient. This study provides further support for the recent report of hyperprolactinemia in some patients with long-standing Meniere's disease and presenting incapacitating vertigo in France. The data emphasize the likely implication of stress in this pathology where the stress hormone prolactin is likely to represent one actor in a complex hormonal imbalance affecting the inner ear. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/895497
- author
- Falkenius-Schmidt, Karolina LU ; Rydmarker, S and Horner, KC
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Meniere's disease, stress, hyperprolactinemia, pituitary adenoma, vertigo, hearing
- in
- Hearing Research
- volume
- 203
- issue
- 1-2
- pages
- 154 - 158
- publisher
- Elsevier
- external identifiers
-
- wos:000229166300017
- pmid:15855040
- scopus:18044386971
- ISSN
- 0378-5955
- DOI
- 10.1016/j.heares.2004.11.015
- language
- English
- LU publication?
- yes
- id
- e4241abc-4561-414f-99a9-3b2d06c8eca5 (old id 895497)
- date added to LUP
- 2016-04-01 12:23:00
- date last changed
- 2022-04-21 06:43:17
@article{e4241abc-4561-414f-99a9-3b2d06c8eca5,
abstract = {{Stress can be a significant factor influencing ear pathologies and is often reported to trigger the symptoms of Meniere's disease. Both physiological and psychological stress provokes the release of prolactin from the pituitary thus allowing the classification of prolactin as a major stress hormone. We investigated the level of the stress hormone prolactin in a Swedish population with early symptoms of Meniere's disease. The median prolactin level in the Meniere patients (n = 33) was not significantly different from that of non-Meniere patients (n = 23). However, in the Meniere group one female (90 year old) had prolactin levels in the upper normal range for women, one male (77 year old) had prolactin levels above the normal limit for men, and a third patient (76 year old female) presented hyper prolactinemia with more than twice the normal level. MR1 confirmed a pituitary adenoma in this patient. This study provides further support for the recent report of hyperprolactinemia in some patients with long-standing Meniere's disease and presenting incapacitating vertigo in France. The data emphasize the likely implication of stress in this pathology where the stress hormone prolactin is likely to represent one actor in a complex hormonal imbalance affecting the inner ear.}},
author = {{Falkenius-Schmidt, Karolina and Rydmarker, S and Horner, KC}},
issn = {{0378-5955}},
keywords = {{Meniere's disease; stress; hyperprolactinemia; pituitary adenoma; vertigo; hearing}},
language = {{eng}},
number = {{1-2}},
pages = {{154--158}},
publisher = {{Elsevier}},
series = {{Hearing Research}},
title = {{Hyperprolactinemia in some Meniere patients even in the absence of incapacitating vertigo}},
url = {{http://dx.doi.org/10.1016/j.heares.2004.11.015}},
doi = {{10.1016/j.heares.2004.11.015}},
volume = {{203}},
year = {{2005}},
}