Chromosomal analysis of primary and metastatic Rous sarcomas in the rat
Mitelman, Felix LU
and Mark, Joachim
(1970)
In Hereditas
65.
p.227-236
- Abstract
- The chromosomes of 13 primary and 4 secondary Rous sarcomas (RSV–SR) in the rat have been studied in fixations directly from the tumour. The general character of the chromosomal spectrum in the primary sarcomas was similar to that of the Rous sarcomas in the mouse and the Chinese hamster. However, normal diploid stemlines were considerably more frequent in the rat sarcomas; among the heteroploid stemlines it was noticeable that polyploids were absent and that pseudodiploidy seemed to be a more important evolutionary pathway than in the mouse and the Chinese hamster. Trends towards a non-random chromosomal engagement were noticed, both in the primary sarcomas and in the metastases derived from them.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/89595a52-90b0-4715-8ab3-8d7b38e59cae
- author
- Mitelman, Felix
LU
and Mark, Joachim
- organization
- publishing date
- 1970
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Hereditas
- volume
- 65
- pages
- 227 - 236
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:0014889940
- ISSN
- 1601-5223
- language
- English
- LU publication?
- yes
- id
- 89595a52-90b0-4715-8ab3-8d7b38e59cae
- alternative location
- https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1601-5223.1970.tb02320.x?sid=nlm%3Apubmed
- date added to LUP
- 2025-07-24 11:21:42
- date last changed
- 2025-07-25 04:02:14
@article{89595a52-90b0-4715-8ab3-8d7b38e59cae,
abstract = {{The chromosomes of 13 primary and 4 secondary Rous sarcomas (RSV–SR) in the rat have been studied in fixations directly from the tumour. The general character of the chromosomal spectrum in the primary sarcomas was similar to that of the Rous sarcomas in the mouse and the Chinese hamster. However, normal diploid stemlines were considerably more frequent in the rat sarcomas; among the heteroploid stemlines it was noticeable that polyploids were absent and that pseudodiploidy seemed to be a more important evolutionary pathway than in the mouse and the Chinese hamster. Trends towards a non-random chromosomal engagement were noticed, both in the primary sarcomas and in the metastases derived from them.}},
author = {{Mitelman, Felix and Mark, Joachim}},
issn = {{1601-5223}},
language = {{eng}},
pages = {{227--236}},
publisher = {{Wiley-Blackwell}},
series = {{Hereditas}},
title = {{Chromosomal analysis of primary and metastatic Rous sarcomas in the rat}},
url = {{https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1601-5223.1970.tb02320.x?sid=nlm%3Apubmed}},
volume = {{65}},
year = {{1970}},
}