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Computer analysis of three-dimensional power angiography images of foetal cerebral, lung and placental circulation in normal and high-risk pregnancy

Dubiel, M ; Breborowicz, GH ; Ropacka, M ; Pietryga, M ; Maulik, D and Gudmundsson, Saemundur LU (2005) In Ultrasound in Medicine and Biology 31(3). p.321-327
Abstract
Three-dimensional (3-D) ultrasound (US) has greatly improved evaluation of organ circulation. The aim of this study was to explore the possible use of this new technique in normal and high-risk pregnancies. Fetal brain, lung and placenta 3-D power Doppler signal intensity were recorded in 115 normal singleton pregnancies (24 to 42 weeks gestation) and in 67 high-risk pregnancies. Mean image pixel signal intensity was calculated for each organ and a brain-lung ratio. In normal pregnancy, placental and lung signal intensity increased until 33, with a rapid decrease after 38, weeks of gestation. Fetal cerebral signal intensity increased with gestational age. Placental and fetal lung signal intensity was significantly lower in high-risk... (More)
Three-dimensional (3-D) ultrasound (US) has greatly improved evaluation of organ circulation. The aim of this study was to explore the possible use of this new technique in normal and high-risk pregnancies. Fetal brain, lung and placenta 3-D power Doppler signal intensity were recorded in 115 normal singleton pregnancies (24 to 42 weeks gestation) and in 67 high-risk pregnancies. Mean image pixel signal intensity was calculated for each organ and a brain-lung ratio. In normal pregnancy, placental and lung signal intensity increased until 33, with a rapid decrease after 38, weeks of gestation. Fetal cerebral signal intensity increased with gestational age. Placental and fetal lung signal intensity was significantly lower in high-risk pregnancies than in the control group, with increased fetal brain and brain-lung ratios. The present results suggest a reduction of placental perfusion after 38 weeks of gestation in normal pregnancy, with redistribution of fetal circulation. Lung signal intensity increased abruptly at 32 weeks of gestation, which might reflect lung maturity. The new method showed signs of centralization of fetal circulation at the end of gestation. The results might suggest a possible clinical use for fetal surveillance in high-risk pregnancies. (Less)
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
three-dimensional, power angiography, fetus, blood flow, computer, pregnancy, analysis, Doppler
in
Ultrasound in Medicine and Biology
volume
31
issue
3
pages
321 - 327
publisher
Elsevier
external identifiers
  • wos:000227591200006
  • pmid:15749554
  • scopus:14744270027
  • pmid:15749554
ISSN
0301-5629
DOI
10.1016/j.ultrasmedbio.2004.12.008
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400)
id
bad0c555-aff2-4c3c-86c9-504231f3c8e9 (old id 897088)
date added to LUP
2016-04-01 12:07:57
date last changed
2020-09-30 02:11:31
@article{bad0c555-aff2-4c3c-86c9-504231f3c8e9,
  abstract     = {Three-dimensional (3-D) ultrasound (US) has greatly improved evaluation of organ circulation. The aim of this study was to explore the possible use of this new technique in normal and high-risk pregnancies. Fetal brain, lung and placenta 3-D power Doppler signal intensity were recorded in 115 normal singleton pregnancies (24 to 42 weeks gestation) and in 67 high-risk pregnancies. Mean image pixel signal intensity was calculated for each organ and a brain-lung ratio. In normal pregnancy, placental and lung signal intensity increased until 33, with a rapid decrease after 38, weeks of gestation. Fetal cerebral signal intensity increased with gestational age. Placental and fetal lung signal intensity was significantly lower in high-risk pregnancies than in the control group, with increased fetal brain and brain-lung ratios. The present results suggest a reduction of placental perfusion after 38 weeks of gestation in normal pregnancy, with redistribution of fetal circulation. Lung signal intensity increased abruptly at 32 weeks of gestation, which might reflect lung maturity. The new method showed signs of centralization of fetal circulation at the end of gestation. The results might suggest a possible clinical use for fetal surveillance in high-risk pregnancies.},
  author       = {Dubiel, M and Breborowicz, GH and Ropacka, M and Pietryga, M and Maulik, D and Gudmundsson, Saemundur},
  issn         = {0301-5629},
  language     = {eng},
  number       = {3},
  pages        = {321--327},
  publisher    = {Elsevier},
  series       = {Ultrasound in Medicine and Biology},
  title        = {Computer analysis of three-dimensional power angiography images of foetal cerebral, lung and placental circulation in normal and high-risk pregnancy},
  url          = {http://dx.doi.org/10.1016/j.ultrasmedbio.2004.12.008},
  doi          = {10.1016/j.ultrasmedbio.2004.12.008},
  volume       = {31},
  year         = {2005},
}