Encapsulation and selective recognition of molecularly imprinted theophylline and 17 ss-estradiol nanoparticles within electrospun polymer nanofibers
Chronakis, Ioannis S. ; Jakob, Alexandra ; Hagstrom, Bengt and Ye, Lei LU
(2006)
In Langmuir
22(21).
p.8960-8965
- Abstract
- Molecularly imprinted nanoparticles are cross-linked polymer colloids containing tailor-made molecular recognition sites. In this study, molecularly imprinted nanoparticles were easily encapsulated within polymer nanofibers using an electrospinning technique to produce a new type of molecular recognition material. Poly(ethylene terephthalate) (PET) was used as the supporting nanofibers matrix to encapsulate theophylline and 17 beta-estradiol imprinted nanoparticles. The composite nanofibers had an average diameter of 150-300 nm, depending on the content of molecularly imprinted nanoparticles. For the theophylline and 17 beta-estradiol imprinted polymers, an optimal loading of molecularly imprinted nanoparticles was 25-37.5 wt % based on... (More)
- Molecularly imprinted nanoparticles are cross-linked polymer colloids containing tailor-made molecular recognition sites. In this study, molecularly imprinted nanoparticles were easily encapsulated within polymer nanofibers using an electrospinning technique to produce a new type of molecular recognition material. Poly(ethylene terephthalate) (PET) was used as the supporting nanofibers matrix to encapsulate theophylline and 17 beta-estradiol imprinted nanoparticles. The composite nanofibers had an average diameter of 150-300 nm, depending on the content of molecularly imprinted nanoparticles. For the theophylline and 17 beta-estradiol imprinted polymers, an optimal loading of molecularly imprinted nanoparticles was 25-37.5 wt % based on PET. The composite nanofibers prepared under these conditions had a well-defined morphology and displayed the best selective target recognition. Our approach of electrospinning-for-molecularly imprinted nanoparticles-encapsulation has unique advantages and opens new application opportunities for molecularly imprinted nanoparticles and electrospun nanofibers. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/389493
- author
- Chronakis, Ioannis S.
; Jakob, Alexandra
; Hagstrom, Bengt
and Ye, Lei
LU
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Langmuir
- volume
- 22
- issue
- 21
- pages
- 8960 - 8965
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- wos:000240954300050
- scopus:33750329522
- pmid:17014141
- ISSN
- 0743-7463
- DOI
- 10.1021/la0613880
- language
- English
- LU publication?
- yes
- id
- 898203c9-7d62-4b6f-a15b-21238098a84b (old id 389493)
- date added to LUP
- 2016-04-01 12:29:44
- date last changed
- 2025-10-14 10:36:03
@article{898203c9-7d62-4b6f-a15b-21238098a84b,
abstract = {{Molecularly imprinted nanoparticles are cross-linked polymer colloids containing tailor-made molecular recognition sites. In this study, molecularly imprinted nanoparticles were easily encapsulated within polymer nanofibers using an electrospinning technique to produce a new type of molecular recognition material. Poly(ethylene terephthalate) (PET) was used as the supporting nanofibers matrix to encapsulate theophylline and 17 beta-estradiol imprinted nanoparticles. The composite nanofibers had an average diameter of 150-300 nm, depending on the content of molecularly imprinted nanoparticles. For the theophylline and 17 beta-estradiol imprinted polymers, an optimal loading of molecularly imprinted nanoparticles was 25-37.5 wt % based on PET. The composite nanofibers prepared under these conditions had a well-defined morphology and displayed the best selective target recognition. Our approach of electrospinning-for-molecularly imprinted nanoparticles-encapsulation has unique advantages and opens new application opportunities for molecularly imprinted nanoparticles and electrospun nanofibers.}},
author = {{Chronakis, Ioannis S. and Jakob, Alexandra and Hagstrom, Bengt and Ye, Lei}},
issn = {{0743-7463}},
language = {{eng}},
number = {{21}},
pages = {{8960--8965}},
publisher = {{The American Chemical Society (ACS)}},
series = {{Langmuir}},
title = {{Encapsulation and selective recognition of molecularly imprinted theophylline and 17 ss-estradiol nanoparticles within electrospun polymer nanofibers}},
url = {{http://dx.doi.org/10.1021/la0613880}},
doi = {{10.1021/la0613880}},
volume = {{22}},
year = {{2006}},
}