A Strategic Review on Carbon Quantum Dots for Cancer-Diagnostics and Treatment
Naik, Kaustubh ; Chaudhary, Shilpi LU ; Ye, Lei LU
and Parmar, Avanish Singh
(2022)
In Frontiers in Bioengineering and Biotechnology
10.
- Abstract
The understanding of the genesis of life-threatening cancer and its invasion calls for urgent development of novel technologies for real-time observations, early diagnosis, and treatment. Quantum dots (QDs) grabbed the spotlight in oncology owing to their excellent photostability, bright fluorescence, high biocompatibility, good electrical and chemical stability with minimum invasiveness. Recently, carbon QDs (CQDs) have become popular over toxic inorganic QDs in the area of bioimaging, biosensing, and drug delivery. Further, CQDs derived from natural sources like biomolecules and medicinal plants have drawn attention because of their one-pot, low-cost and ease of synthesis, along with remarkable tunable optical properties and... (More)
The understanding of the genesis of life-threatening cancer and its invasion calls for urgent development of novel technologies for real-time observations, early diagnosis, and treatment. Quantum dots (QDs) grabbed the spotlight in oncology owing to their excellent photostability, bright fluorescence, high biocompatibility, good electrical and chemical stability with minimum invasiveness. Recently, carbon QDs (CQDs) have become popular over toxic inorganic QDs in the area of bioimaging, biosensing, and drug delivery. Further, CQDs derived from natural sources like biomolecules and medicinal plants have drawn attention because of their one-pot, low-cost and ease of synthesis, along with remarkable tunable optical properties and biocompatibility. This review introduces the synthesis and properties of CQDs derived from natural sources, focusing on the applicability of CQD-based technologies as nano-theranostics for the diagnosis and treatment of cancer. Furthermore, the current issues and future directions for the transformation of CQDs-based nanotechnologies to clinical applications are highlighted.
(Less)
- author
- Naik, Kaustubh
; Chaudhary, Shilpi
LU
; Ye, Lei
LU
and Parmar, Avanish Singh
- organization
- publishing date
- 2022-05-18
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- bioimaging, cancer, carbon quantum dots, drug delivery, photoinduced absorption
- in
- Frontiers in Bioengineering and Biotechnology
- volume
- 10
- article number
- 882100
- pages
- 21 pages
- publisher
- Frontiers Media S. A.
- external identifiers
-
- pmid:35662840
- scopus:85131522061
- ISSN
- 2296-4185
- DOI
- 10.3389/fbioe.2022.882100
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: Copyright © 2022 Naik, Chaudhary, Ye and Parmar.
- id
- 89880c75-2689-49fa-997e-135f77d2fcf1
- date added to LUP
- 2022-09-29 14:23:43
- date last changed
- 2024-04-18 15:27:13
@article{89880c75-2689-49fa-997e-135f77d2fcf1,
abstract = {{<p>The understanding of the genesis of life-threatening cancer and its invasion calls for urgent development of novel technologies for real-time observations, early diagnosis, and treatment. Quantum dots (QDs) grabbed the spotlight in oncology owing to their excellent photostability, bright fluorescence, high biocompatibility, good electrical and chemical stability with minimum invasiveness. Recently, carbon QDs (CQDs) have become popular over toxic inorganic QDs in the area of bioimaging, biosensing, and drug delivery. Further, CQDs derived from natural sources like biomolecules and medicinal plants have drawn attention because of their one-pot, low-cost and ease of synthesis, along with remarkable tunable optical properties and biocompatibility. This review introduces the synthesis and properties of CQDs derived from natural sources, focusing on the applicability of CQD-based technologies as nano-theranostics for the diagnosis and treatment of cancer. Furthermore, the current issues and future directions for the transformation of CQDs-based nanotechnologies to clinical applications are highlighted.</p>}},
author = {{Naik, Kaustubh and Chaudhary, Shilpi and Ye, Lei and Parmar, Avanish Singh}},
issn = {{2296-4185}},
keywords = {{bioimaging; cancer; carbon quantum dots; drug delivery; photoinduced absorption}},
language = {{eng}},
month = {{05}},
publisher = {{Frontiers Media S. A.}},
series = {{Frontiers in Bioengineering and Biotechnology}},
title = {{A Strategic Review on Carbon Quantum Dots for Cancer-Diagnostics and Treatment}},
url = {{http://dx.doi.org/10.3389/fbioe.2022.882100}},
doi = {{10.3389/fbioe.2022.882100}},
volume = {{10}},
year = {{2022}},
}