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Quantification of ovarian power Doppler signal with three-dimensional ultrasonography to predict response during in vitro fertilization

Jarvela, IY; Sladkevicius, Povilas LU ; Kelly, S; Ojha, K; Campbell, S and Nargund, G (2003) In Obstetrics and Gynecology 102(4). p.816-822
Abstract
OBJECTIVE: To evaluate whether power Doppler predicts ovarian response to gonadotrophin stimulation during in vitro fertilization (IVF). METHODS: Forty-five women were divided into low-reserve (n = 12) and normal-reserve (n = 33) ovarian groups, according to antral follicle count. Transvaginal three-dimensional power Doppler ultrasonographic examinations were performed after pituitary downregulation and after gonadotrophin stimulation. The antral follicle count, ovarian volume, vascularization index, flow index, vascularization flow index, and mean gray value were measured and related to the number of oocytes retrieved and the pregnancy rate. RESULTS: The number of oocytes retrieved correlated with the antral follicle count (R = .4581, P =... (More)
OBJECTIVE: To evaluate whether power Doppler predicts ovarian response to gonadotrophin stimulation during in vitro fertilization (IVF). METHODS: Forty-five women were divided into low-reserve (n = 12) and normal-reserve (n = 33) ovarian groups, according to antral follicle count. Transvaginal three-dimensional power Doppler ultrasonographic examinations were performed after pituitary downregulation and after gonadotrophin stimulation. The antral follicle count, ovarian volume, vascularization index, flow index, vascularization flow index, and mean gray value were measured and related to the number of oocytes retrieved and the pregnancy rate. RESULTS: The number of oocytes retrieved correlated with the antral follicle count (R = .4581, P = .004) and ovarian volume (R = .389, P < .016) but not with vascularization index, flow index, vascularization flow index, or mean gray value after pituitary suppression. There was an increase in vascularization index (P < .017), flow index (P < .001), and vascularization flow index (P < .007) during gonadotrophin stimulation in the normal-ovary group but not in the low-ovarian-reserve group. CONCLUSION: According to our results, quantification of power Doppler signal in the ovaries after pituitary suppression does not provide any additional information to predict the subsequent response to gonadotrophin stimulation during IVY The increase in ovarian power Doppler signal during gonadotrophin stimulation is related to the antral follicle count observed after pituitary suppression. (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
in
Obstetrics and Gynecology
volume
102
issue
4
pages
816 - 822
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:14551013
  • wos:000185746000025
  • scopus:0141459444
ISSN
1873-233X
DOI
language
English
LU publication?
yes
id
ea162764-f4cc-4f03-bb48-7449deb915a7 (old id 899881)
date added to LUP
2008-01-14 14:06:00
date last changed
2018-05-29 09:29:07
@article{ea162764-f4cc-4f03-bb48-7449deb915a7,
  abstract     = {OBJECTIVE: To evaluate whether power Doppler predicts ovarian response to gonadotrophin stimulation during in vitro fertilization (IVF). METHODS: Forty-five women were divided into low-reserve (n = 12) and normal-reserve (n = 33) ovarian groups, according to antral follicle count. Transvaginal three-dimensional power Doppler ultrasonographic examinations were performed after pituitary downregulation and after gonadotrophin stimulation. The antral follicle count, ovarian volume, vascularization index, flow index, vascularization flow index, and mean gray value were measured and related to the number of oocytes retrieved and the pregnancy rate. RESULTS: The number of oocytes retrieved correlated with the antral follicle count (R = .4581, P = .004) and ovarian volume (R = .389, P &lt; .016) but not with vascularization index, flow index, vascularization flow index, or mean gray value after pituitary suppression. There was an increase in vascularization index (P &lt; .017), flow index (P &lt; .001), and vascularization flow index (P &lt; .007) during gonadotrophin stimulation in the normal-ovary group but not in the low-ovarian-reserve group. CONCLUSION: According to our results, quantification of power Doppler signal in the ovaries after pituitary suppression does not provide any additional information to predict the subsequent response to gonadotrophin stimulation during IVY The increase in ovarian power Doppler signal during gonadotrophin stimulation is related to the antral follicle count observed after pituitary suppression.},
  author       = {Jarvela, IY and Sladkevicius, Povilas and Kelly, S and Ojha, K and Campbell, S and Nargund, G},
  issn         = {1873-233X},
  language     = {eng},
  number       = {4},
  pages        = {816--822},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {Obstetrics and Gynecology},
  title        = {Quantification of ovarian power Doppler signal with three-dimensional ultrasonography to predict response during in vitro fertilization},
  url          = {http://dx.doi.org/},
  volume       = {102},
  year         = {2003},
}