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Filamentary keratopathy: A non-contact photomicrographic in vivo study in the human cornea

Tabery, Helena LU (2003) In European Journal of Ophthalmology 13(7). p.599-605
Abstract
PURPOSE. To investigate in vivo morphology of corneal filaments. MATERIALS AND METHODS. Over a 12-year period, 19 patients with corneal filaments (7 with keratoconjunctivitis sicca and 12 with other surface diseases) were examined with the slit lamp and photographed by non-contact photomicrography. RESULTS. The filaments appeared as variously long and thick threads, attached at one or both ends to the surface and carrying various amounts of granular and amorphous material. The attachment points and their surroundings showed abnormal cells and diffusion of tear fluid stained green with fluorescein sodium. The underlying stroma appeared normal. The remaining epithelium often showed abnormal surface cells and/or edematous or cystic changes.... (More)
PURPOSE. To investigate in vivo morphology of corneal filaments. MATERIALS AND METHODS. Over a 12-year period, 19 patients with corneal filaments (7 with keratoconjunctivitis sicca and 12 with other surface diseases) were examined with the slit lamp and photographed by non-contact photomicrography. RESULTS. The filaments appeared as variously long and thick threads, attached at one or both ends to the surface and carrying various amounts of granular and amorphous material. The attachment points and their surroundings showed abnormal cells and diffusion of tear fluid stained green with fluorescein sodium. The underlying stroma appeared normal. The remaining epithelium often showed abnormal surface cells and/or edematous or cystic changes. CONCLUSIONS. The in vivo morphology of filamentary keratopathy is consistent with aggregations of mucus and cell debris adhering to the corneal surface. The underlying diseases seem to have in common corneal epithelial edema. The nature of additional factors, or their combination, precipitating mucus adherence to the surface is not clear. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
filaments, cornea, human
in
European Journal of Ophthalmology
volume
13
issue
7
pages
599 - 605
publisher
Wichtig Editore
external identifiers
  • wos:000185674800001
  • scopus:0141892120
ISSN
1120-6721
language
English
LU publication?
yes
id
8615aafb-67f7-4cf4-b4e3-ce0afda3e451 (old id 899905)
alternative location
http://www.eur-j-ophthalmol.com/ejo/index.asp?a=abstract&id=924E665C-D384-4B2D-96BC-4936E59
date added to LUP
2008-01-16 09:53:25
date last changed
2018-01-07 05:09:12
@article{8615aafb-67f7-4cf4-b4e3-ce0afda3e451,
  abstract     = {PURPOSE. To investigate in vivo morphology of corneal filaments. MATERIALS AND METHODS. Over a 12-year period, 19 patients with corneal filaments (7 with keratoconjunctivitis sicca and 12 with other surface diseases) were examined with the slit lamp and photographed by non-contact photomicrography. RESULTS. The filaments appeared as variously long and thick threads, attached at one or both ends to the surface and carrying various amounts of granular and amorphous material. The attachment points and their surroundings showed abnormal cells and diffusion of tear fluid stained green with fluorescein sodium. The underlying stroma appeared normal. The remaining epithelium often showed abnormal surface cells and/or edematous or cystic changes. CONCLUSIONS. The in vivo morphology of filamentary keratopathy is consistent with aggregations of mucus and cell debris adhering to the corneal surface. The underlying diseases seem to have in common corneal epithelial edema. The nature of additional factors, or their combination, precipitating mucus adherence to the surface is not clear.},
  author       = {Tabery, Helena},
  issn         = {1120-6721},
  keyword      = {filaments,cornea,human},
  language     = {eng},
  number       = {7},
  pages        = {599--605},
  publisher    = {Wichtig Editore},
  series       = {European Journal of Ophthalmology},
  title        = {Filamentary keratopathy: A non-contact photomicrographic in vivo study in the human cornea},
  volume       = {13},
  year         = {2003},
}