Synthesis and characterization of a six-coordinate monomeric Mn(III) complex with SOD-like activity
(2006) In Journal of Coordination Chemistry 59(2). p.119-130- Abstract
- The complex [Mn-III(HL)(L)(py)(CH3OH)](CH3OH)-C-. (H2L=2-ortho-hydroxyphenylbenzimidazole, py pyridine), 1, has been characterized spectroscopically and by X-ray crystallography. The complex is triclinic, space group P-1(-) with a = 10.396(2), b = 10.7340(10), c = 15.193(2) angstrom, alpha = 73.193(4)degrees, beta = 76.283(8)degrees, gamma = 61.400(40)degrees, V = 1415.1(4)angstrom(3), Z = 2, D-c = 1.445 Mg m(-3), M-r = 615.56, mu = 0.515 mm(-1), F(000) = 640, R = 0.0631, wR = 0.1525. Manganese is six-coordinate in an N3O3 ligand sphere created by two bidentate H2L ligands and solvent molecules with a slightly distorted, axially elongated octahedral geometry. Electronic absorption spectra show pi-pi* and Ligand Metal Charge Transfer (LMCT)... (More)
- The complex [Mn-III(HL)(L)(py)(CH3OH)](CH3OH)-C-. (H2L=2-ortho-hydroxyphenylbenzimidazole, py pyridine), 1, has been characterized spectroscopically and by X-ray crystallography. The complex is triclinic, space group P-1(-) with a = 10.396(2), b = 10.7340(10), c = 15.193(2) angstrom, alpha = 73.193(4)degrees, beta = 76.283(8)degrees, gamma = 61.400(40)degrees, V = 1415.1(4)angstrom(3), Z = 2, D-c = 1.445 Mg m(-3), M-r = 615.56, mu = 0.515 mm(-1), F(000) = 640, R = 0.0631, wR = 0.1525. Manganese is six-coordinate in an N3O3 ligand sphere created by two bidentate H2L ligands and solvent molecules with a slightly distorted, axially elongated octahedral geometry. Electronic absorption spectra show pi-pi* and Ligand Metal Charge Transfer (LMCT) transitions in the UV region and d-d transitions in the visible region. Solvent molecules coordinated to the Mn(III) ion in the crystal are thought to retain their coordination in solution. It is shown that 1 has reaction activity with the superoxide ion, as indicated by inhibition of pyrogallol autoxidation and by spin trapping electron paramagnetic resonance (EPR) spectroscopy. The N3O3 ligand set in 1 is similar to that in native MnSOD (superoxide dismutatase) in the substrate-bound state. The correlation between the ligand set in 1 and its reaction with the superoxide ion is discussed. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/417110
- author
- Shi, W ; Liu, Y ; Liu, B ; Song, YG ; Xu, YK ; Wang, HM ; Sha, YL ; Xu, GZ ; Styring, Stenbjörn LU and Huang, P
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- 2-dimethyl-3, 4-dihydro-2H-pyrrole-1-oxide, spin trap, pyrogallol, autoxidation, 2, superoxide ion reactivity, superoxide dismutase, structure, X-ray, pyridine, Manganese(III), 2-o-hydroxyphenylbenzimidazole
- in
- Journal of Coordination Chemistry
- volume
- 59
- issue
- 2
- pages
- 119 - 130
- publisher
- Taylor & Francis
- external identifiers
-
- wos:000235500600001
- scopus:29044438159
- ISSN
- 1026-7441
- DOI
- 10.1080/00958970500249814
- language
- English
- LU publication?
- yes
- id
- 8a9edf47-7a6b-437f-b863-14c0db2d870c (old id 417110)
- date added to LUP
- 2016-04-01 12:29:36
- date last changed
- 2022-01-27 05:48:45
@article{8a9edf47-7a6b-437f-b863-14c0db2d870c,
abstract = {{The complex [Mn-III(HL)(L)(py)(CH3OH)](CH3OH)-C-. (H2L=2-ortho-hydroxyphenylbenzimidazole, py pyridine), 1, has been characterized spectroscopically and by X-ray crystallography. The complex is triclinic, space group P-1(-) with a = 10.396(2), b = 10.7340(10), c = 15.193(2) angstrom, alpha = 73.193(4)degrees, beta = 76.283(8)degrees, gamma = 61.400(40)degrees, V = 1415.1(4)angstrom(3), Z = 2, D-c = 1.445 Mg m(-3), M-r = 615.56, mu = 0.515 mm(-1), F(000) = 640, R = 0.0631, wR = 0.1525. Manganese is six-coordinate in an N3O3 ligand sphere created by two bidentate H2L ligands and solvent molecules with a slightly distorted, axially elongated octahedral geometry. Electronic absorption spectra show pi-pi* and Ligand Metal Charge Transfer (LMCT) transitions in the UV region and d-d transitions in the visible region. Solvent molecules coordinated to the Mn(III) ion in the crystal are thought to retain their coordination in solution. It is shown that 1 has reaction activity with the superoxide ion, as indicated by inhibition of pyrogallol autoxidation and by spin trapping electron paramagnetic resonance (EPR) spectroscopy. The N3O3 ligand set in 1 is similar to that in native MnSOD (superoxide dismutatase) in the substrate-bound state. The correlation between the ligand set in 1 and its reaction with the superoxide ion is discussed.}},
author = {{Shi, W and Liu, Y and Liu, B and Song, YG and Xu, YK and Wang, HM and Sha, YL and Xu, GZ and Styring, Stenbjörn and Huang, P}},
issn = {{1026-7441}},
keywords = {{2-dimethyl-3; 4-dihydro-2H-pyrrole-1-oxide; spin trap; pyrogallol; autoxidation; 2; superoxide ion reactivity; superoxide dismutase; structure; X-ray; pyridine; Manganese(III); 2-o-hydroxyphenylbenzimidazole}},
language = {{eng}},
number = {{2}},
pages = {{119--130}},
publisher = {{Taylor & Francis}},
series = {{Journal of Coordination Chemistry}},
title = {{Synthesis and characterization of a six-coordinate monomeric Mn(III) complex with SOD-like activity}},
url = {{http://dx.doi.org/10.1080/00958970500249814}},
doi = {{10.1080/00958970500249814}},
volume = {{59}},
year = {{2006}},
}