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Twelve-Single Nucleotide Polymorphism Genetic Risk Score Identifies Individuals at Increased Risk for Future Atrial Fibrillation and Stroke.

Tada, Hayato ; Shiffman, Dov ; Smith, Gustav LU ; Sjögren, Marketa LU ; Lubitz, Steven A ; Ellinor, Patrick T ; Louie, Judy Z ; Catanese, Joseph J ; Engström, Gunnar LU and Devlin, James J , et al. (2014) In Stroke: a journal of cerebral circulation 45(10). p.2856-2856
Abstract
Atrial fibrillation (AF) is prevalent and there is a clinical need for biomarkers to identify individuals at higher risk for AF. Fixed throughout a life course and assayable early in life, genetic biomarkers may meet this need. Here, we investigate whether multiple single nucleotide polymorphisms together as an AF genetic risk score (AF-GRS) can improve prediction of one's risk for AF.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Stroke: a journal of cerebral circulation
volume
45
issue
10
pages
2856 - 2856
publisher
American Heart Association
external identifiers
  • pmid:25123217
  • wos:000342794700014
  • scopus:84922480103
  • pmid:25123217
ISSN
1524-4628
DOI
10.1161/STROKEAHA.114.006072
language
English
LU publication?
yes
id
8b5c7bc0-6742-4445-83d9-c9bcd9804b46 (old id 4614688)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25123217?dopt=Abstract
date added to LUP
2016-04-01 10:35:26
date last changed
2024-01-06 20:28:34
@article{8b5c7bc0-6742-4445-83d9-c9bcd9804b46,
  abstract     = {{Atrial fibrillation (AF) is prevalent and there is a clinical need for biomarkers to identify individuals at higher risk for AF. Fixed throughout a life course and assayable early in life, genetic biomarkers may meet this need. Here, we investigate whether multiple single nucleotide polymorphisms together as an AF genetic risk score (AF-GRS) can improve prediction of one's risk for AF.}},
  author       = {{Tada, Hayato and Shiffman, Dov and Smith, Gustav and Sjögren, Marketa and Lubitz, Steven A and Ellinor, Patrick T and Louie, Judy Z and Catanese, Joseph J and Engström, Gunnar and Devlin, James J and Kathiresan, Sekar and Melander, Olle}},
  issn         = {{1524-4628}},
  language     = {{eng}},
  number       = {{10}},
  pages        = {{2856--2856}},
  publisher    = {{American Heart Association}},
  series       = {{Stroke: a journal of cerebral circulation}},
  title        = {{Twelve-Single Nucleotide Polymorphism Genetic Risk Score Identifies Individuals at Increased Risk for Future Atrial Fibrillation and Stroke.}},
  url          = {{http://dx.doi.org/10.1161/STROKEAHA.114.006072}},
  doi          = {{10.1161/STROKEAHA.114.006072}},
  volume       = {{45}},
  year         = {{2014}},
}