Risk of schizophrenia in second-generation immigrants: a Danish population-based cohort study.
(2007) In Psychological Medicine 37(4). p.485-494- Abstract
- Background. Urban birth, a risk factor for schizophrenia, is more frequent among secondgeneration
immigrants. The aim of the current study was to determine whether the increased risk
for schizophrenia found in second-generation immigrants is explained by the degree of urbanization
of birthplace and/or factors related to parentage, such as geographic origin or history of residence
abroad during upbringing.
Method. Using data from the Danish Civil Registration System (CRS), we established a
population-based cohort of 2.0 million Danes (persons born in Denmark). Schizophrenia in cohort
members was identified by cross-linkage with the Danish Psychiatric Central Register.
... (More) - Background. Urban birth, a risk factor for schizophrenia, is more frequent among secondgeneration
immigrants. The aim of the current study was to determine whether the increased risk
for schizophrenia found in second-generation immigrants is explained by the degree of urbanization
of birthplace and/or factors related to parentage, such as geographic origin or history of residence
abroad during upbringing.
Method. Using data from the Danish Civil Registration System (CRS), we established a
population-based cohort of 2.0 million Danes (persons born in Denmark). Schizophrenia in cohort
members was identified by cross-linkage with the Danish Psychiatric Central Register.
Results. The relative risk of developing schizophrenia was 1.93 [95% confidence interval (CI)
1.79–2.08] and 2.96 (95% CI 2.49–3.51) among persons with one or both parents foreign-born
respectively compared to native Danes. Adjustment for urbanization of birthplace and parental
characteristics reduced these risks slightly. However, urbanization had a lesser effect in secondgeneration
immigrants than in Danes. History of residence abroad was a risk factor for schizophrenia,
regardless of whether parents were foreign-born or native Danes.
Conclusion. The increased risk found in second-generation immigrants cannot be explained by
urbanization or parental characteristics pertaining to age, mental illness, geographic origin or
residence abroad during a child’s upbringing. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/165160
- author
- Cantor-Graae, Elizabeth LU and Pedersen, Carsten B
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Psychological Medicine
- volume
- 37
- issue
- 4
- pages
- 485 - 494
- publisher
- Cambridge University Press
- external identifiers
-
- wos:000245535900004
- scopus:33847706988
- pmid:17202000
- ISSN
- 1469-8978
- DOI
- 10.1017/S0033291706009652
- language
- English
- LU publication?
- yes
- id
- 8b958c25-ade6-4ea7-b770-1ee036d0fefc (old id 165160)
- date added to LUP
- 2016-04-01 12:21:23
- date last changed
- 2022-01-27 02:37:34
@article{8b958c25-ade6-4ea7-b770-1ee036d0fefc,
abstract = {{Background. Urban birth, a risk factor for schizophrenia, is more frequent among secondgeneration<br/><br>
immigrants. The aim of the current study was to determine whether the increased risk<br/><br>
for schizophrenia found in second-generation immigrants is explained by the degree of urbanization<br/><br>
of birthplace and/or factors related to parentage, such as geographic origin or history of residence<br/><br>
abroad during upbringing.<br/><br>
Method. Using data from the Danish Civil Registration System (CRS), we established a<br/><br>
population-based cohort of 2.0 million Danes (persons born in Denmark). Schizophrenia in cohort<br/><br>
members was identified by cross-linkage with the Danish Psychiatric Central Register.<br/><br>
Results. The relative risk of developing schizophrenia was 1.93 [95% confidence interval (CI)<br/><br>
1.79–2.08] and 2.96 (95% CI 2.49–3.51) among persons with one or both parents foreign-born<br/><br>
respectively compared to native Danes. Adjustment for urbanization of birthplace and parental<br/><br>
characteristics reduced these risks slightly. However, urbanization had a lesser effect in secondgeneration<br/><br>
immigrants than in Danes. History of residence abroad was a risk factor for schizophrenia,<br/><br>
regardless of whether parents were foreign-born or native Danes.<br/><br>
Conclusion. The increased risk found in second-generation immigrants cannot be explained by<br/><br>
urbanization or parental characteristics pertaining to age, mental illness, geographic origin or<br/><br>
residence abroad during a child’s upbringing.}},
author = {{Cantor-Graae, Elizabeth and Pedersen, Carsten B}},
issn = {{1469-8978}},
language = {{eng}},
number = {{4}},
pages = {{485--494}},
publisher = {{Cambridge University Press}},
series = {{Psychological Medicine}},
title = {{Risk of schizophrenia in second-generation immigrants: a Danish population-based cohort study.}},
url = {{http://dx.doi.org/10.1017/S0033291706009652}},
doi = {{10.1017/S0033291706009652}},
volume = {{37}},
year = {{2007}},
}