Population based cohort study of the association between alcohol intake and cancer of the upper digestive tract
(1998) In British Medical Journal 317(7162). p.844-848- Abstract
Objective: To examine the relation between different types of alcoholic drinks and upper digestive tract cancers (oropharyngeal and oesophageal). Design: Population based study with baseline assessment of intake of beer, wine, and spirits, smoking habits, educational level, and 2-19 years' follow up on risk of upper digestive tract cancer. Setting: Denmark. Subjects: 15,117 men and 13,063 women aged 20 to 98 years. Main outcome measure: Number and time of identification of incident upper digestive tract cancer during follow up. Results: During a mean follow up of 13.5 years, 156 subjects developed upper digestive tract cancer. Compared with non-drinkers (drinkers of < 1 drink/week), subjects who drank 7-21 beers or spirits a week but... (More)
Objective: To examine the relation between different types of alcoholic drinks and upper digestive tract cancers (oropharyngeal and oesophageal). Design: Population based study with baseline assessment of intake of beer, wine, and spirits, smoking habits, educational level, and 2-19 years' follow up on risk of upper digestive tract cancer. Setting: Denmark. Subjects: 15,117 men and 13,063 women aged 20 to 98 years. Main outcome measure: Number and time of identification of incident upper digestive tract cancer during follow up. Results: During a mean follow up of 13.5 years, 156 subjects developed upper digestive tract cancer. Compared with non-drinkers (drinkers of < 1 drink/week), subjects who drank 7-21 beers or spirits a week but no wine were at a risk of 3.0 (95% confidence interval 1.5 to 6.1), whereas those who had the same total alcohol intake but with wine as ≤ 30% of their intake had a risk of 0.5 (0.2 to 1.4). Drinkers of > 21 beers and spirits but no wine had a relative risk of 5.2 (2.7 to 10.2) compared with non-drinkers, whereas those who drank the same amount, but included wine in their alcohol intake, had a relative risk of 1.7 (0.6 to 4.1). Conclusion: A moderate intake of wine probably does not increase the risk of upper digestive tract cancer, whereas a moderate intake of beer or spirits increases the risk considerably.
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- author
- Grønbæk, Morten ; Becker, Ulrik ; Johansen, Ditte ; Tønnesen, Hanne LU ; Jensen, Gorm and Sørensen, Thorkild I.A.
- publishing date
- 1998-09-26
- type
- Contribution to journal
- publication status
- published
- in
- British Medical Journal
- volume
- 317
- issue
- 7162
- pages
- 5 pages
- publisher
- BMJ Publishing Group
- external identifiers
-
- scopus:0032569438
- pmid:9748175
- ISSN
- 0959-8146
- DOI
- 10.1136/bmj.317.7162.844
- language
- English
- LU publication?
- no
- id
- 8cc24684-63cf-467d-a097-faf3d9363b5b
- date added to LUP
- 2022-10-27 16:52:43
- date last changed
- 2024-06-13 20:27:06
@article{8cc24684-63cf-467d-a097-faf3d9363b5b,
abstract = {{<p>Objective: To examine the relation between different types of alcoholic drinks and upper digestive tract cancers (oropharyngeal and oesophageal). Design: Population based study with baseline assessment of intake of beer, wine, and spirits, smoking habits, educational level, and 2-19 years' follow up on risk of upper digestive tract cancer. Setting: Denmark. Subjects: 15,117 men and 13,063 women aged 20 to 98 years. Main outcome measure: Number and time of identification of incident upper digestive tract cancer during follow up. Results: During a mean follow up of 13.5 years, 156 subjects developed upper digestive tract cancer. Compared with non-drinkers (drinkers of < 1 drink/week), subjects who drank 7-21 beers or spirits a week but no wine were at a risk of 3.0 (95% confidence interval 1.5 to 6.1), whereas those who had the same total alcohol intake but with wine as ≤ 30% of their intake had a risk of 0.5 (0.2 to 1.4). Drinkers of > 21 beers and spirits but no wine had a relative risk of 5.2 (2.7 to 10.2) compared with non-drinkers, whereas those who drank the same amount, but included wine in their alcohol intake, had a relative risk of 1.7 (0.6 to 4.1). Conclusion: A moderate intake of wine probably does not increase the risk of upper digestive tract cancer, whereas a moderate intake of beer or spirits increases the risk considerably.</p>}},
author = {{Grønbæk, Morten and Becker, Ulrik and Johansen, Ditte and Tønnesen, Hanne and Jensen, Gorm and Sørensen, Thorkild I.A.}},
issn = {{0959-8146}},
language = {{eng}},
month = {{09}},
number = {{7162}},
pages = {{844--848}},
publisher = {{BMJ Publishing Group}},
series = {{British Medical Journal}},
title = {{Population based cohort study of the association between alcohol intake and cancer of the upper digestive tract}},
url = {{http://dx.doi.org/10.1136/bmj.317.7162.844}},
doi = {{10.1136/bmj.317.7162.844}},
volume = {{317}},
year = {{1998}},
}