The effect of capsaicin on some experimental inflammations in human skin.
(1986) In Acta Dermato-Venereologica 66(5). p.375-380- Abstract
- Topical application of capsaicin is thought to deplete substance P from local sensory nerve terminals. In experiments on human skin inflammation was induced by injection of substance P (SP) or histamine intradermally, UV irradiation, non-immunologic contact urticaria, tuberculin reaction, contact allergens and benzalkonium chloride with or without capsaicin pretreatment. The flare response to SP and histamine was suppressed by capsaicin pretreatment whereas the wheal was enlarged. Interestingly, capsaicin pretreatment enhanced the responses to all other inflammatory agents.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8d61810a-b992-44de-a8c9-24a28fe92011
- author
- Wallengren, Joanna LU and Möller, Halvor LU
- organization
- publishing date
- 1986
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Dermato-Venereologica
- volume
- 66
- issue
- 5
- pages
- 375 - 380
- publisher
- Medical Journals Limited
- external identifiers
-
- scopus:0022966528
- ISSN
- 1651-2057
- language
- English
- LU publication?
- yes
- id
- 8d61810a-b992-44de-a8c9-24a28fe92011
- date added to LUP
- 2019-07-25 15:26:16
- date last changed
- 2021-10-23 04:03:10
@article{8d61810a-b992-44de-a8c9-24a28fe92011, abstract = {{Topical application of capsaicin is thought to deplete substance P from local sensory nerve terminals. In experiments on human skin inflammation was induced by injection of substance P (SP) or histamine intradermally, UV irradiation, non-immunologic contact urticaria, tuberculin reaction, contact allergens and benzalkonium chloride with or without capsaicin pretreatment. The flare response to SP and histamine was suppressed by capsaicin pretreatment whereas the wheal was enlarged. Interestingly, capsaicin pretreatment enhanced the responses to all other inflammatory agents.}}, author = {{Wallengren, Joanna and Möller, Halvor}}, issn = {{1651-2057}}, language = {{eng}}, number = {{5}}, pages = {{375--380}}, publisher = {{Medical Journals Limited}}, series = {{Acta Dermato-Venereologica}}, title = {{The effect of capsaicin on some experimental inflammations in human skin.}}, volume = {{66}}, year = {{1986}}, }