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The effect of capsaicin on some experimental inflammations in human skin.

Wallengren, Joanna LU orcid and Möller, Halvor LU (1986) In Acta Dermato-Venereologica 66(5). p.375-380
Abstract
Topical application of capsaicin is thought to deplete substance P from local sensory nerve terminals. In experiments on human skin inflammation was induced by injection of substance P (SP) or histamine intradermally, UV irradiation, non-immunologic contact urticaria, tuberculin reaction, contact allergens and benzalkonium chloride with or without capsaicin pretreatment. The flare response to SP and histamine was suppressed by capsaicin pretreatment whereas the wheal was enlarged. Interestingly, capsaicin pretreatment enhanced the responses to all other inflammatory agents.
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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Dermato-Venereologica
volume
66
issue
5
pages
375 - 380
publisher
Medical Journals Limited
external identifiers
  • scopus:0022966528
ISSN
1651-2057
language
English
LU publication?
yes
id
8d61810a-b992-44de-a8c9-24a28fe92011
date added to LUP
2019-07-25 15:26:16
date last changed
2021-10-23 04:03:10
@article{8d61810a-b992-44de-a8c9-24a28fe92011,
  abstract     = {{Topical application of capsaicin is thought to deplete substance P from local sensory nerve terminals. In experiments on human skin inflammation was induced by injection of substance P (SP) or histamine intradermally, UV irradiation, non-immunologic contact urticaria, tuberculin reaction, contact allergens and benzalkonium chloride with or without capsaicin pretreatment. The flare response to SP and histamine was suppressed by capsaicin pretreatment whereas the wheal was enlarged. Interestingly, capsaicin pretreatment enhanced the responses to all other inflammatory agents.}},
  author       = {{Wallengren, Joanna and Möller, Halvor}},
  issn         = {{1651-2057}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{375--380}},
  publisher    = {{Medical Journals Limited}},
  series       = {{Acta Dermato-Venereologica}},
  title        = {{The effect of capsaicin on some experimental inflammations in human skin.}},
  volume       = {{66}},
  year         = {{1986}},
}