Risk factors for pelvic inflammatory diseases among Swedish women aged 15 years or older : A nationwide cohort study (2002–2018)
(2026) In Heliyon 12(1).- Abstract
Objectives This study aimed to examine associations of sociodemographic factors, cervical cancer, urogenital infections (cystitis, vulvovaginitis, and vaginosis), and parity with pelvic inflammatory diseases (PID). Methods Nationwide open cohort study including 4,097,075 women aged 15 years or older during the study time period (2002–2018). Cox proportional hazard regression models were used to estimate Hazard ratios (HR) and 95 % confidence intervals (CI) for the first event of PID during the study period. Results Young age, low education, low family income, cervical cancer, other urogenital infections, and parity were independently associated with a higher risk of PID. In addition to young age, the risks of PID were particularly... (More)
Objectives This study aimed to examine associations of sociodemographic factors, cervical cancer, urogenital infections (cystitis, vulvovaginitis, and vaginosis), and parity with pelvic inflammatory diseases (PID). Methods Nationwide open cohort study including 4,097,075 women aged 15 years or older during the study time period (2002–2018). Cox proportional hazard regression models were used to estimate Hazard ratios (HR) and 95 % confidence intervals (CI) for the first event of PID during the study period. Results Young age, low education, low family income, cervical cancer, other urogenital infections, and parity were independently associated with a higher risk of PID. In addition to young age, the risks of PID were particularly elevated amongst women with cervical cancer (HR 2.02; 95 % CI 1.82–2.23) and urogenital infections such as vaginosis (HR 2.60; 95 % CI 2.55–2.65) compared to those without these conditions. Conclusion The elevated PID risk linked to sociodemographic factors, cervical cancer, and urogenital infections indicates areas for preventive measures and screening efforts. These findings may be used by clinicians to identify women at increased risk of PID and indicate areas for enhanced screening efforts and preventive measures in public health programs.
(Less)
- author
- Forsberg, Per Ola
LU
; Sundqvist, Christoffer
LU
; Li, Xinjun
LU
; Borgfeldt, Christer
LU
; Sundquist, Kristina
LU
and Jansåker, Filip
LU
- organization
-
- Family Medicine and Clinical Epidemiology (research group)
- Department of Clinical Sciences, Malmö
- LUCC: Lund University Cancer Centre
- Gynecological Cancer and Cancer prevention as well as prevention of Osteoporosis (research group)
- Obstetrics and Gynaecology (Lund)
- EpiHealth: Epidemiology for Health
- publishing date
- 2026-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Cervical cancer, Cystitis, Pelvic inflammatory diseases, Socioeconomic status, Vaginosis, Vulvovaginitis
- in
- Heliyon
- volume
- 12
- issue
- 1
- article number
- e44429
- publisher
- Elsevier
- external identifiers
-
- scopus:105025650610
- ISSN
- 2405-8440
- DOI
- 10.1016/j.heliyon.2025.e44429
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: Copyright © 2025. Published by Elsevier Ltd.
- id
- 8dce2173-4720-4589-a842-860f5cfc10a4
- date added to LUP
- 2026-03-24 14:36:24
- date last changed
- 2026-03-24 14:37:05
@article{8dce2173-4720-4589-a842-860f5cfc10a4,
abstract = {{<p>Objectives This study aimed to examine associations of sociodemographic factors, cervical cancer, urogenital infections (cystitis, vulvovaginitis, and vaginosis), and parity with pelvic inflammatory diseases (PID). Methods Nationwide open cohort study including 4,097,075 women aged 15 years or older during the study time period (2002–2018). Cox proportional hazard regression models were used to estimate Hazard ratios (HR) and 95 % confidence intervals (CI) for the first event of PID during the study period. Results Young age, low education, low family income, cervical cancer, other urogenital infections, and parity were independently associated with a higher risk of PID. In addition to young age, the risks of PID were particularly elevated amongst women with cervical cancer (HR 2.02; 95 % CI 1.82–2.23) and urogenital infections such as vaginosis (HR 2.60; 95 % CI 2.55–2.65) compared to those without these conditions. Conclusion The elevated PID risk linked to sociodemographic factors, cervical cancer, and urogenital infections indicates areas for preventive measures and screening efforts. These findings may be used by clinicians to identify women at increased risk of PID and indicate areas for enhanced screening efforts and preventive measures in public health programs.</p>}},
author = {{Forsberg, Per Ola and Sundqvist, Christoffer and Li, Xinjun and Borgfeldt, Christer and Sundquist, Kristina and Jansåker, Filip}},
issn = {{2405-8440}},
keywords = {{Cervical cancer; Cystitis; Pelvic inflammatory diseases; Socioeconomic status; Vaginosis; Vulvovaginitis}},
language = {{eng}},
number = {{1}},
publisher = {{Elsevier}},
series = {{Heliyon}},
title = {{Risk factors for pelvic inflammatory diseases among Swedish women aged 15 years or older : A nationwide cohort study (2002–2018)}},
url = {{http://dx.doi.org/10.1016/j.heliyon.2025.e44429}},
doi = {{10.1016/j.heliyon.2025.e44429}},
volume = {{12}},
year = {{2026}},
}