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Monitoring Low Molecular Weight Heparins at Therapeutic Levels: Dose-Responses of, and Correlations and Differences between aPTT, Anti-Factor Xa and Thrombin Generation Assays.

Thomas, Owain LU orcid ; Lybeck, Emanuel LU ; Strandberg, Karin LU ; Tynngård, Nahreen and Schött, Ulf LU (2015) In PLoS ONE 10(1).
Abstract
Low molecular weight heparins (LMWH's) are used to prevent and treat thrombosis. Tests for monitoring LMWH's include anti-factor Xa (anti-FXa), activated partial thromboplastin time (aPTT) and thrombin generation. Anti-FXa is the current gold standard despite LMWH's varying affinities for FXa and thrombin.
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
10
issue
1
article number
e0116835
publisher
Public Library of Science (PLoS)
external identifiers
  • pmid:25625201
  • wos:000348821400018
  • scopus:84921969922
  • pmid:25625201
ISSN
1932-6203
DOI
10.1371/journal.pone.0116835
project
Koagulation vid kirurgi och kritisk sjukdom
Haemostatic Safety in Epidural Analgesia
language
English
LU publication?
yes
id
8e2ba9de-9387-4a07-8d65-3dc0a76955c1 (old id 5039555)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25625201?dopt=Abstract
date added to LUP
2016-04-01 13:20:00
date last changed
2022-05-07 08:45:30
@article{8e2ba9de-9387-4a07-8d65-3dc0a76955c1,
  abstract     = {{Low molecular weight heparins (LMWH's) are used to prevent and treat thrombosis. Tests for monitoring LMWH's include anti-factor Xa (anti-FXa), activated partial thromboplastin time (aPTT) and thrombin generation. Anti-FXa is the current gold standard despite LMWH's varying affinities for FXa and thrombin.}},
  author       = {{Thomas, Owain and Lybeck, Emanuel and Strandberg, Karin and Tynngård, Nahreen and Schött, Ulf}},
  issn         = {{1932-6203}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{Public Library of Science (PLoS)}},
  series       = {{PLoS ONE}},
  title        = {{Monitoring Low Molecular Weight Heparins at Therapeutic Levels: Dose-Responses of, and Correlations and Differences between aPTT, Anti-Factor Xa and Thrombin Generation Assays.}},
  url          = {{https://lup.lub.lu.se/search/files/3307114/7753794}},
  doi          = {{10.1371/journal.pone.0116835}},
  volume       = {{10}},
  year         = {{2015}},
}