Ribotyping of Clostridium difficile strains associated with nosocomial transmission and relapses in a Swedish County
(2013) In APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 121(2). p.153-157- Abstract
- Clostridium difficile is an emerging threat in hospital environments. To analyse possible transmission and to distinguish between relapse and reinfection a collection of C. difficile isolates, sampled from 162 consecutive episodes of C. difficile infection, were PCR ribotyped. Two ribotypes (001 and 012) were prone to cause nosocomial acquisition. Moreover, ribotype 001 had a tendency to cause relapses as almost one in two patients with this ribotype had one or more relapses. By using PCR ribotyping strains inclined to cause relapses and strains associated with hospital transmission might be detected. This enables optimized hygiene measures and may improve the choice of treatment regimen.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3590934
- author
- Magnusson, Cecilia ; Wullt, Marlene LU ; Lofgren, Sture ; Iveroth, Peter ; Akerlund, Tomas and Matussek, Andreas
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Clostridium difficile, molecular epidemiology, ribotyping, transmission, CDI, hygiene measures
- in
- APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
- volume
- 121
- issue
- 2
- pages
- 153 - 157
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000313830700009
- scopus:84872665873
- pmid:23030627
- ISSN
- 1600-0463
- DOI
- 10.1111/j.1600-0463.2012.02950.x
- language
- English
- LU publication?
- yes
- id
- 8fa036f6-e086-4d9a-944d-d3450ae622c5 (old id 3590934)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23030627
- date added to LUP
- 2016-04-01 10:13:15
- date last changed
- 2022-04-12 03:13:00
@article{8fa036f6-e086-4d9a-944d-d3450ae622c5, abstract = {{Clostridium difficile is an emerging threat in hospital environments. To analyse possible transmission and to distinguish between relapse and reinfection a collection of C. difficile isolates, sampled from 162 consecutive episodes of C. difficile infection, were PCR ribotyped. Two ribotypes (001 and 012) were prone to cause nosocomial acquisition. Moreover, ribotype 001 had a tendency to cause relapses as almost one in two patients with this ribotype had one or more relapses. By using PCR ribotyping strains inclined to cause relapses and strains associated with hospital transmission might be detected. This enables optimized hygiene measures and may improve the choice of treatment regimen.}}, author = {{Magnusson, Cecilia and Wullt, Marlene and Lofgren, Sture and Iveroth, Peter and Akerlund, Tomas and Matussek, Andreas}}, issn = {{1600-0463}}, keywords = {{Clostridium difficile; molecular epidemiology; ribotyping; transmission; CDI; hygiene measures}}, language = {{eng}}, number = {{2}}, pages = {{153--157}}, publisher = {{John Wiley & Sons Inc.}}, series = {{APMIS : acta pathologica, microbiologica, et immunologica Scandinavica}}, title = {{Ribotyping of Clostridium difficile strains associated with nosocomial transmission and relapses in a Swedish County}}, url = {{http://dx.doi.org/10.1111/j.1600-0463.2012.02950.x}}, doi = {{10.1111/j.1600-0463.2012.02950.x}}, volume = {{121}}, year = {{2013}}, }