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Cell-based therapy for Parkinson's disease : A journey through decades toward the light side of the Force

Parmar, Malin LU ; Torper, Olof LU and Drouin-Ouellet, Janelle LU (2018) In European Journal of Neuroscience
Abstract

This review describes the history, development, and evolution of cell-based replacement therapy for Parkinson's disease (PD), from the first pioneering trials with fetal ventral midbrain progenitors to future trials using stem cells as well as reprogrammed cells. In the spirit of Tom Isaacs, the review takes parallels to the storyline of Star Wars, including the temptations from the dark side and the continuous fight for the light side of the Force. It is subdivided into headings based on the original movies, spanning from A New Hope to the Last Jedi.

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author
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
cell reprogramming, human embryonic stem cells, human-induced pluripotent stem cells, induced neurons, Parkinson's disease, Star Wars, transplantation
in
European Journal of Neuroscience
publisher
Wiley-Blackwell
external identifiers
  • scopus:85053324584
ISSN
0953-816X
DOI
10.1111/ejn.14109
language
English
LU publication?
yes
id
8fdc8bc3-e4f1-4dc4-a332-b9676f65519a
date added to LUP
2018-10-22 12:38:42
date last changed
2019-04-13 02:17:14
@article{8fdc8bc3-e4f1-4dc4-a332-b9676f65519a,
  abstract     = {<p>This review describes the history, development, and evolution of cell-based replacement therapy for Parkinson's disease (PD), from the first pioneering trials with fetal ventral midbrain progenitors to future trials using stem cells as well as reprogrammed cells. In the spirit of Tom Isaacs, the review takes parallels to the storyline of Star Wars, including the temptations from the dark side and the continuous fight for the light side of the Force. It is subdivided into headings based on the original movies, spanning from A New Hope to the Last Jedi.</p>},
  author       = {Parmar, Malin and Torper, Olof and Drouin-Ouellet, Janelle},
  issn         = {0953-816X},
  keyword      = {cell reprogramming,human embryonic stem cells,human-induced pluripotent stem cells,induced neurons,Parkinson's disease,Star Wars,transplantation},
  language     = {eng},
  month        = {08},
  publisher    = {Wiley-Blackwell},
  series       = {European Journal of Neuroscience},
  title        = {Cell-based therapy for Parkinson's disease : A journey through decades toward the light side of the Force},
  url          = {http://dx.doi.org/10.1111/ejn.14109},
  year         = {2018},
}