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Adaptive regulation of lipoprotein lipase and salt-resistant lipase activities in essential fatty acid deficiency. An experimental study in the rat.

Nilsson, Åke LU ; Hjelte, Lena ; Nilsson-Ehle, Peter LU and Strandvik, Birgitta (1990) In Metabolism 39(12). p.1305-1308
Abstract
Lipoprotein lipase (LPL) activities of postheparin plasma, heart, lungs, and adipose tissue, and salt-resistant lipase (hepatic lipase, SRL) activities of postheparin plasma, liver, and adrenals were examined in essential fatty acid deficient (EFAD) rats and in age-matched controls. The LPL activity of heart was higher in the deficient than in the control rats, but did not differ in the other tissues. The SRL activity of postheparin plasma was twofold higher, and that of liver and adrenals approximately 50% higher in the group with EFA deficiency. It is suggested that SRL exhibits an adaptive up-regulation in EFA deficiency. This up-regulation may be linked to a role for the enzyme in the transport of polyenoic fatty acids.
Abstract (Swedish)
Lipoprotein lipase (LPL) activities of postheparin plasma, heart, lungs, and adipose tissue, and salt-resistant lipase (hepatic lipase, SRL) activities of postheparin plasma, liver, and adrenals were examined in essential fatty acid deficient (EFAD) rats and in age-matched controls. The LPL activity of heart was higher in the deficient than in the control rats, but did not differ in the other tissues. The SRL activity of postheparin plasma was twofold higher, and that of liver and adrenals approximately 50% higher in the group with EFA deficiency. It is suggested that SRL exhibits an adaptive up-regulation in EFA deficiency. This up-regulation may be linked to a role for the enzyme in the transport of polyenoic fatty acids.
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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Metabolism
volume
39
issue
12
pages
1305 - 1308
publisher
Elsevier
external identifiers
  • scopus:0025666891
  • pmid:2246972
DOI
10.1016/0026-0495(90)90188-I
language
English
LU publication?
yes
id
8fde0512-b0cb-4ccd-a94c-a47bfe4e59be
date added to LUP
2019-05-24 10:39:01
date last changed
2024-01-01 07:31:58
@article{8fde0512-b0cb-4ccd-a94c-a47bfe4e59be,
  abstract     = {{Lipoprotein lipase (LPL) activities of postheparin plasma, heart, lungs, and adipose tissue, and salt-resistant lipase (hepatic lipase, SRL) activities of postheparin plasma, liver, and adrenals were examined in essential fatty acid deficient (EFAD) rats and in age-matched controls. The LPL activity of heart was higher in the deficient than in the control rats, but did not differ in the other tissues. The SRL activity of postheparin plasma was twofold higher, and that of liver and adrenals approximately 50% higher in the group with EFA deficiency. It is suggested that SRL exhibits an adaptive up-regulation in EFA deficiency. This up-regulation may be linked to a role for the enzyme in the transport of polyenoic fatty acids.}},
  author       = {{Nilsson, Åke and Hjelte, Lena and Nilsson-Ehle, Peter and Strandvik, Birgitta}},
  language     = {{eng}},
  month        = {{12}},
  number       = {{12}},
  pages        = {{1305--1308}},
  publisher    = {{Elsevier}},
  series       = {{Metabolism}},
  title        = {{Adaptive regulation of lipoprotein lipase and salt-resistant lipase activities in essential fatty acid deficiency. An experimental study in the rat.}},
  url          = {{http://dx.doi.org/10.1016/0026-0495(90)90188-I}},
  doi          = {{10.1016/0026-0495(90)90188-I}},
  volume       = {{39}},
  year         = {{1990}},
}