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Evaluation of fetal circulation redistribution in pregnancies with absent or reversed diastolic flow in the umbilical artery

Dubiel, M; Breborowicz, GH and Gudmundsson, Saemundur LU (2003) In Early Human Development 71(2). p.149-156
Abstract
Aim: To record blood flow velocimetry in the superior mesenteric, hepatic and middle cerebral arteries for detection of circulation redistribution and prediction of perinatal outcome in fetuses with absent or reversed diastolic flow in the umbilical artery. Study design: The fetal superior mesenteric, hepatic and middle cerebral artery blood velocimetry was recorded in 33 pregnancies complicated by pregnancy-induced hypertension and/or intra-uterine growth retardation between 27 and 41 weeks of gestation. Uterine artery and umbilical vein velocimetries were also recorded. Results: An abnormal mesenteric artery pulsatility, index (PI) was found in four cases; two newborns died due to prematurity, growth retardation and necrotizing... (More)
Aim: To record blood flow velocimetry in the superior mesenteric, hepatic and middle cerebral arteries for detection of circulation redistribution and prediction of perinatal outcome in fetuses with absent or reversed diastolic flow in the umbilical artery. Study design: The fetal superior mesenteric, hepatic and middle cerebral artery blood velocimetry was recorded in 33 pregnancies complicated by pregnancy-induced hypertension and/or intra-uterine growth retardation between 27 and 41 weeks of gestation. Uterine artery and umbilical vein velocimetries were also recorded. Results: An abnormal mesenteric artery pulsatility, index (PI) was found in four cases; two newborns died due to prematurity, growth retardation and necrotizing enterocolitis. An abnormal fetal hepatic artery PI was found in 17 cases. The brain-sparing effect in the middle cerebral artery was found in 16 cases; three newborns died after delivery. Signs of redistribution in mesenteric, hepatic and middle cerebral artery velocimetry were not related to most of the perinatal outcome variables. Umbilical vein velocimetry correlated with low arterial and venous pH. All perinatal mortalities had umbilical venous pulsations. Conclusions: Signs of visceral circulation redistribution could not predict adverse outcome. Umbilical venous pulsations were, however, seen in nearly all fetuses; this was the only variable suggesting adverse outcome in the present study of severely compromised fetuses. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
velocimetry, diastolic flow, umbilical artery
in
Early Human Development
volume
71
issue
2
pages
149 - 156
publisher
Elsevier
external identifiers
  • pmid:12663152
  • wos:000182284900006
  • scopus:0037379045
ISSN
1872-6232
DOI
10.1016/S0378-3782(03)00006-9
language
English
LU publication?
yes
id
5a430fdf-4f5f-4b3d-980b-a6405f174816 (old id 900464)
date added to LUP
2008-01-10 19:27:36
date last changed
2017-02-19 04:19:57
@article{5a430fdf-4f5f-4b3d-980b-a6405f174816,
  abstract     = {Aim: To record blood flow velocimetry in the superior mesenteric, hepatic and middle cerebral arteries for detection of circulation redistribution and prediction of perinatal outcome in fetuses with absent or reversed diastolic flow in the umbilical artery. Study design: The fetal superior mesenteric, hepatic and middle cerebral artery blood velocimetry was recorded in 33 pregnancies complicated by pregnancy-induced hypertension and/or intra-uterine growth retardation between 27 and 41 weeks of gestation. Uterine artery and umbilical vein velocimetries were also recorded. Results: An abnormal mesenteric artery pulsatility, index (PI) was found in four cases; two newborns died due to prematurity, growth retardation and necrotizing enterocolitis. An abnormal fetal hepatic artery PI was found in 17 cases. The brain-sparing effect in the middle cerebral artery was found in 16 cases; three newborns died after delivery. Signs of redistribution in mesenteric, hepatic and middle cerebral artery velocimetry were not related to most of the perinatal outcome variables. Umbilical vein velocimetry correlated with low arterial and venous pH. All perinatal mortalities had umbilical venous pulsations. Conclusions: Signs of visceral circulation redistribution could not predict adverse outcome. Umbilical venous pulsations were, however, seen in nearly all fetuses; this was the only variable suggesting adverse outcome in the present study of severely compromised fetuses. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.},
  author       = {Dubiel, M and Breborowicz, GH and Gudmundsson, Saemundur},
  issn         = {1872-6232},
  keyword      = {velocimetry,diastolic flow,umbilical artery},
  language     = {eng},
  number       = {2},
  pages        = {149--156},
  publisher    = {Elsevier},
  series       = {Early Human Development},
  title        = {Evaluation of fetal circulation redistribution in pregnancies with absent or reversed diastolic flow in the umbilical artery},
  url          = {http://dx.doi.org/10.1016/S0378-3782(03)00006-9},
  volume       = {71},
  year         = {2003},
}