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Laser therapy for refractory discoid lupus erythematosus when everything else has failed

Ekback, Maria Palmetun and Troilius, Agneta LU (2013) In Journal of Cosmetic & Laser Therapy 15(5). p.260-265
Abstract
Background: Discoid lupus erythematosus (DLE) is restricted to the skin, mostly the face, often chronic and disfiguring. Standard medical therapies include topical corticosteroids and antimalarials. This is a retrospective long-term follow-up of refractory DLE treated with different lasers and intense pulsed light (IPL). Methods and materials : Sixteen patients with histologically confirmed DLE participated in this study. Two men and fourteen women, aged 28-69 years, mean age 54 years, were treated at the laser units of the Departments of Dermatology at the University Hospital of Orebro from 2001 and at Skane University Hospital in Malmo, Sweden from 1999. Several therapies, including first- and secondline treatments and even cryotherapy,... (More)
Background: Discoid lupus erythematosus (DLE) is restricted to the skin, mostly the face, often chronic and disfiguring. Standard medical therapies include topical corticosteroids and antimalarials. This is a retrospective long-term follow-up of refractory DLE treated with different lasers and intense pulsed light (IPL). Methods and materials : Sixteen patients with histologically confirmed DLE participated in this study. Two men and fourteen women, aged 28-69 years, mean age 54 years, were treated at the laser units of the Departments of Dermatology at the University Hospital of Orebro from 2001 and at Skane University Hospital in Malmo, Sweden from 1999. Several therapies, including first- and secondline treatments and even cryotherapy, had been used without response. Many patients had marked scarring. Pulsed dye laser (PDL) and IPL were used with low fluencies. Results: Of 16 patients, 14 were improved regarding itching, erythema, scaling, scarring and pain. There was no scarring as a side effect of laser therapy or IPL. Two patients were not satisfied: one because of long healing time, and the other because of post inflammatory hyper pigmentation. Conclusion: IPL and PDL is a safe adjunctive therapy to conventional treatment of DLE. In the effort to prevent severe scarring and disfigurement it should be used as early as possible. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cosmetic, discoid lupus erythematosus, intense pulsed light, laser, pulsed dye laser, therapy resistant
in
Journal of Cosmetic & Laser Therapy
volume
15
issue
5
pages
260 - 265
publisher
Informa Healthcare
external identifiers
  • wos:000324483000004
  • scopus:84884245854
  • pmid:23607738
ISSN
1476-4172
DOI
10.3109/14764172.2013.787802
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Dermatology and Venerology (013241320)
id
9064b397-bc8a-4031-aaa5-418804827d99 (old id 4106320)
date added to LUP
2016-04-01 10:47:24
date last changed
2020-01-12 05:35:58
@article{9064b397-bc8a-4031-aaa5-418804827d99,
  abstract     = {Background: Discoid lupus erythematosus (DLE) is restricted to the skin, mostly the face, often chronic and disfiguring. Standard medical therapies include topical corticosteroids and antimalarials. This is a retrospective long-term follow-up of refractory DLE treated with different lasers and intense pulsed light (IPL). Methods and materials : Sixteen patients with histologically confirmed DLE participated in this study. Two men and fourteen women, aged 28-69 years, mean age 54 years, were treated at the laser units of the Departments of Dermatology at the University Hospital of Orebro from 2001 and at Skane University Hospital in Malmo, Sweden from 1999. Several therapies, including first- and secondline treatments and even cryotherapy, had been used without response. Many patients had marked scarring. Pulsed dye laser (PDL) and IPL were used with low fluencies. Results: Of 16 patients, 14 were improved regarding itching, erythema, scaling, scarring and pain. There was no scarring as a side effect of laser therapy or IPL. Two patients were not satisfied: one because of long healing time, and the other because of post inflammatory hyper pigmentation. Conclusion: IPL and PDL is a safe adjunctive therapy to conventional treatment of DLE. In the effort to prevent severe scarring and disfigurement it should be used as early as possible.},
  author       = {Ekback, Maria Palmetun and Troilius, Agneta},
  issn         = {1476-4172},
  language     = {eng},
  number       = {5},
  pages        = {260--265},
  publisher    = {Informa Healthcare},
  series       = {Journal of Cosmetic & Laser Therapy},
  title        = {Laser therapy for refractory discoid lupus erythematosus when everything else has failed},
  url          = {http://dx.doi.org/10.3109/14764172.2013.787802},
  doi          = {10.3109/14764172.2013.787802},
  volume       = {15},
  year         = {2013},
}