Potential and utilization of thermophiles and thermostable enzymes in biorefining
Turner, Pernilla LU ; Mamo, Gashaw LU and Nordberg Karlsson, Eva LU
(2007)
In Microbial Cell Factories
6.
- Abstract
- In today's world, there is an increasing trend towards the use of renewable, cheap and readily available biomass in the production of a wide variety of fine and bulk chemicals in different biorefineries. Biorefineries utilize the activities of microbial cells and their enzymes to convert biomass into target products. Many of these processes require enzymes which are operationally stable at high temperature thus allowing e. g. easy mixing, better substrate solubility, high mass transfer rate, and lowered risk of contamination. Thermophiles have often been proposed as sources of industrially relevant thermostable enzymes. Here we discuss existing and potential applications of thermophiles and thermostable enzymes with focus on conversion of... (More)
- In today's world, there is an increasing trend towards the use of renewable, cheap and readily available biomass in the production of a wide variety of fine and bulk chemicals in different biorefineries. Biorefineries utilize the activities of microbial cells and their enzymes to convert biomass into target products. Many of these processes require enzymes which are operationally stable at high temperature thus allowing e. g. easy mixing, better substrate solubility, high mass transfer rate, and lowered risk of contamination. Thermophiles have often been proposed as sources of industrially relevant thermostable enzymes. Here we discuss existing and potential applications of thermophiles and thermostable enzymes with focus on conversion of carbohydrate containing raw materials. Their importance in biorefineries is explained using examples of lignocellulose and starch conversions to desired products. Strategies that enhance thermostablity of enzymes both in vivo and in vitro are also assessed. Moreover, this review deals with efforts made on developing vectors for expressing recombinant enzymes in thermophilic hosts. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/666377
- author
- Turner, Pernilla
LU
; Mamo, Gashaw
LU
and Nordberg Karlsson, Eva
LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Microbial Cell Factories
- volume
- 6
- publisher
- BioMed Central (BMC)
- external identifiers
-
- wos:000245594400001
- scopus:34147150667
- ISSN
- 1475-2859
- DOI
- 10.1186/1475-2859-6-9
- language
- English
- LU publication?
- yes
- id
- 90f9eade-f765-4a84-b237-c30162d8c4ca (old id 666377)
- date added to LUP
- 2016-04-01 16:45:51
- date last changed
- 2022-04-23 00:12:05
@article{90f9eade-f765-4a84-b237-c30162d8c4ca,
abstract = {{In today's world, there is an increasing trend towards the use of renewable, cheap and readily available biomass in the production of a wide variety of fine and bulk chemicals in different biorefineries. Biorefineries utilize the activities of microbial cells and their enzymes to convert biomass into target products. Many of these processes require enzymes which are operationally stable at high temperature thus allowing e. g. easy mixing, better substrate solubility, high mass transfer rate, and lowered risk of contamination. Thermophiles have often been proposed as sources of industrially relevant thermostable enzymes. Here we discuss existing and potential applications of thermophiles and thermostable enzymes with focus on conversion of carbohydrate containing raw materials. Their importance in biorefineries is explained using examples of lignocellulose and starch conversions to desired products. Strategies that enhance thermostablity of enzymes both in vivo and in vitro are also assessed. Moreover, this review deals with efforts made on developing vectors for expressing recombinant enzymes in thermophilic hosts.}},
author = {{Turner, Pernilla and Mamo, Gashaw and Nordberg Karlsson, Eva}},
issn = {{1475-2859}},
language = {{eng}},
publisher = {{BioMed Central (BMC)}},
series = {{Microbial Cell Factories}},
title = {{Potential and utilization of thermophiles and thermostable enzymes in biorefining}},
url = {{http://dx.doi.org/10.1186/1475-2859-6-9}},
doi = {{10.1186/1475-2859-6-9}},
volume = {{6}},
year = {{2007}},
}