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Acousto-optic interaction strengths in optically scattering media using high pressure acoustic pulses

Hill, David LU ; Bengtsson, Alexander LU ; Erlov, Tobias LU ; Cinthio, Magnus LU and Kroll, Stefan LU (2021) In Biomedical Optics Express 12(6). p.3196-3213
Abstract

Ultrasound optical tomography (UOT) is a developing medical imaging technique with the potential to noninvasively image tissue oxygenation at depths of several centimeters in human tissue. To accurately model the UOT imaging, it is necessary the calculate the signal produced by the interaction between ultrasound and light in the scattering medium. In this paper we present a rigorous description for modeling this process for ultrasound pulses in the non-linear regime with peak pressures ranging up to the medical safety limit. Simulation results based on the presented model agree well with measurements performed with fully characterized ultrasound pulses. Our results also indicate that the UOT modeling process can be accurately simplified... (More)

Ultrasound optical tomography (UOT) is a developing medical imaging technique with the potential to noninvasively image tissue oxygenation at depths of several centimeters in human tissue. To accurately model the UOT imaging, it is necessary the calculate the signal produced by the interaction between ultrasound and light in the scattering medium. In this paper we present a rigorous description for modeling this process for ultrasound pulses in the non-linear regime with peak pressures ranging up to the medical safety limit. Simulation results based on the presented model agree well with measurements performed with fully characterized ultrasound pulses. Our results also indicate that the UOT modeling process can be accurately simplified by disregarding the acoustically induced movement of scatterers. Our results suggest that the explored model and its software implementation can be used as a virtual lab to aid future development of pulses and UOT imaging algorithms.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Biomedical Optics Express
volume
12
issue
6
pages
18 pages
publisher
Optical Society of America
external identifiers
  • scopus:85106372658
  • pmid:34221654
ISSN
2156-7085
DOI
10.1364/BOE.421636
language
English
LU publication?
yes
additional info
Funding Information: Funding. Knut and Alice Wallenberg Foundation (KAW) (2016.0081); Lund University Faculty of Engineering; Wallenberg Centre for Quantum Technology (WACQT) funded by the Knut and Alice Wallenberg Foundation (2017.0449); Smarter Electronic Systems, a collaborative venture by Vinnova, Formas, and Swedish Energy Agency (2019-02110). Publisher Copyright: © 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
id
91b1773e-2d2d-48dc-9aa4-ce61095ab42b
date added to LUP
2021-07-05 08:03:07
date last changed
2024-06-29 14:18:49
@article{91b1773e-2d2d-48dc-9aa4-ce61095ab42b,
  abstract     = {{<p>Ultrasound optical tomography (UOT) is a developing medical imaging technique with the potential to noninvasively image tissue oxygenation at depths of several centimeters in human tissue. To accurately model the UOT imaging, it is necessary the calculate the signal produced by the interaction between ultrasound and light in the scattering medium. In this paper we present a rigorous description for modeling this process for ultrasound pulses in the non-linear regime with peak pressures ranging up to the medical safety limit. Simulation results based on the presented model agree well with measurements performed with fully characterized ultrasound pulses. Our results also indicate that the UOT modeling process can be accurately simplified by disregarding the acoustically induced movement of scatterers. Our results suggest that the explored model and its software implementation can be used as a virtual lab to aid future development of pulses and UOT imaging algorithms.</p>}},
  author       = {{Hill, David and Bengtsson, Alexander and Erlov, Tobias and Cinthio, Magnus and Kroll, Stefan}},
  issn         = {{2156-7085}},
  language     = {{eng}},
  month        = {{06}},
  number       = {{6}},
  pages        = {{3196--3213}},
  publisher    = {{Optical Society of America}},
  series       = {{Biomedical Optics Express}},
  title        = {{Acousto-optic interaction strengths in optically scattering media using high pressure acoustic pulses}},
  url          = {{http://dx.doi.org/10.1364/BOE.421636}},
  doi          = {{10.1364/BOE.421636}},
  volume       = {{12}},
  year         = {{2021}},
}