Acousto-optic interaction strengths in optically scattering media using high pressure acoustic pulses
(2021) In Biomedical Optics Express 12(6). p.3196-3213- Abstract
Ultrasound optical tomography (UOT) is a developing medical imaging technique with the potential to noninvasively image tissue oxygenation at depths of several centimeters in human tissue. To accurately model the UOT imaging, it is necessary the calculate the signal produced by the interaction between ultrasound and light in the scattering medium. In this paper we present a rigorous description for modeling this process for ultrasound pulses in the non-linear regime with peak pressures ranging up to the medical safety limit. Simulation results based on the presented model agree well with measurements performed with fully characterized ultrasound pulses. Our results also indicate that the UOT modeling process can be accurately simplified... (More)
Ultrasound optical tomography (UOT) is a developing medical imaging technique with the potential to noninvasively image tissue oxygenation at depths of several centimeters in human tissue. To accurately model the UOT imaging, it is necessary the calculate the signal produced by the interaction between ultrasound and light in the scattering medium. In this paper we present a rigorous description for modeling this process for ultrasound pulses in the non-linear regime with peak pressures ranging up to the medical safety limit. Simulation results based on the presented model agree well with measurements performed with fully characterized ultrasound pulses. Our results also indicate that the UOT modeling process can be accurately simplified by disregarding the acoustically induced movement of scatterers. Our results suggest that the explored model and its software implementation can be used as a virtual lab to aid future development of pulses and UOT imaging algorithms.
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- author
- Hill, David LU ; Bengtsson, Alexander LU ; Erlov, Tobias LU ; Cinthio, Magnus LU and Kroll, Stefan LU
- organization
- publishing date
- 2021-06-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Biomedical Optics Express
- volume
- 12
- issue
- 6
- pages
- 18 pages
- publisher
- Optical Society of America
- external identifiers
-
- scopus:85106372658
- pmid:34221654
- ISSN
- 2156-7085
- DOI
- 10.1364/BOE.421636
- language
- English
- LU publication?
- yes
- additional info
- Funding Information: Funding. Knut and Alice Wallenberg Foundation (KAW) (2016.0081); Lund University Faculty of Engineering; Wallenberg Centre for Quantum Technology (WACQT) funded by the Knut and Alice Wallenberg Foundation (2017.0449); Smarter Electronic Systems, a collaborative venture by Vinnova, Formas, and Swedish Energy Agency (2019-02110). Publisher Copyright: © 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
- id
- 91b1773e-2d2d-48dc-9aa4-ce61095ab42b
- date added to LUP
- 2021-07-05 08:03:07
- date last changed
- 2024-06-29 14:18:49
@article{91b1773e-2d2d-48dc-9aa4-ce61095ab42b, abstract = {{<p>Ultrasound optical tomography (UOT) is a developing medical imaging technique with the potential to noninvasively image tissue oxygenation at depths of several centimeters in human tissue. To accurately model the UOT imaging, it is necessary the calculate the signal produced by the interaction between ultrasound and light in the scattering medium. In this paper we present a rigorous description for modeling this process for ultrasound pulses in the non-linear regime with peak pressures ranging up to the medical safety limit. Simulation results based on the presented model agree well with measurements performed with fully characterized ultrasound pulses. Our results also indicate that the UOT modeling process can be accurately simplified by disregarding the acoustically induced movement of scatterers. Our results suggest that the explored model and its software implementation can be used as a virtual lab to aid future development of pulses and UOT imaging algorithms.</p>}}, author = {{Hill, David and Bengtsson, Alexander and Erlov, Tobias and Cinthio, Magnus and Kroll, Stefan}}, issn = {{2156-7085}}, language = {{eng}}, month = {{06}}, number = {{6}}, pages = {{3196--3213}}, publisher = {{Optical Society of America}}, series = {{Biomedical Optics Express}}, title = {{Acousto-optic interaction strengths in optically scattering media using high pressure acoustic pulses}}, url = {{http://dx.doi.org/10.1364/BOE.421636}}, doi = {{10.1364/BOE.421636}}, volume = {{12}}, year = {{2021}}, }