Update in antibiotic therapy in intensive care unit : report from the 2019 Nîmes International Symposium
(2019) In Anaesthesia Critical Care & Pain Medicine 38(6). p.647-656- Abstract
The 2019 Nîmes International Symposium in Antibiotic Therapy Optimisation aimed at determining the best approaches of a number of the antibiotic management strategies for critically ill patients. Experts reviewed the latest literature relating to requirements for an optimal antibiotic stewardship program, risks of sub-therapeutic dosing of antibiotics in critically ill patients, persisting issues about efficiency of combination therapy and the value of de-escalation, new perspectives of pharmacokinetics, drug toxicities including collateral damages-associated with antibiotics, the place of nebulisation of antibiotics, management of patients receiving extracorporeal therapies and the place of new antibiotics. In this paper, each of these... (More)
The 2019 Nîmes International Symposium in Antibiotic Therapy Optimisation aimed at determining the best approaches of a number of the antibiotic management strategies for critically ill patients. Experts reviewed the latest literature relating to requirements for an optimal antibiotic stewardship program, risks of sub-therapeutic dosing of antibiotics in critically ill patients, persisting issues about efficiency of combination therapy and the value of de-escalation, new perspectives of pharmacokinetics, drug toxicities including collateral damages-associated with antibiotics, the place of nebulisation of antibiotics, management of patients receiving extracorporeal therapies and the place of new antibiotics. In this paper, each of these issues is discussed with key messages presented after a brief review of evidence.
(Less)
- author
- organization
- publishing date
- 2019-10-10
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Antibiotics, De-escalation, Dosing, Sepsis, Stewardship
- in
- Anaesthesia Critical Care & Pain Medicine
- volume
- 38
- issue
- 6
- pages
- 647 - 656
- publisher
- Elsevier Masson SAS
- external identifiers
-
- scopus:85074481073
- pmid:31606548
- ISSN
- 2352-5568
- DOI
- 10.1016/j.accpm.2019.09.009
- language
- English
- LU publication?
- yes
- id
- 91e9142f-9bea-4247-b04e-9591172f0591
- date added to LUP
- 2019-11-27 13:56:28
- date last changed
- 2024-05-15 02:42:04
@article{91e9142f-9bea-4247-b04e-9591172f0591, abstract = {{<p>The 2019 Nîmes International Symposium in Antibiotic Therapy Optimisation aimed at determining the best approaches of a number of the antibiotic management strategies for critically ill patients. Experts reviewed the latest literature relating to requirements for an optimal antibiotic stewardship program, risks of sub-therapeutic dosing of antibiotics in critically ill patients, persisting issues about efficiency of combination therapy and the value of de-escalation, new perspectives of pharmacokinetics, drug toxicities including collateral damages-associated with antibiotics, the place of nebulisation of antibiotics, management of patients receiving extracorporeal therapies and the place of new antibiotics. In this paper, each of these issues is discussed with key messages presented after a brief review of evidence.</p>}}, author = {{Leone, Marc and Roberts, Jason A. and Bassetti, Matteo and Bouglé, Adrien and Lavigne, Jean Philippe and Legrand, Matthieu and Neely, Michael and Paiva, José Artur and Payen, Didier and Rello, Jordi and Roger, Claire and Sjövall, Fredrik and Jung, Boris}}, issn = {{2352-5568}}, keywords = {{Antibiotics; De-escalation; Dosing; Sepsis; Stewardship}}, language = {{eng}}, month = {{10}}, number = {{6}}, pages = {{647--656}}, publisher = {{Elsevier Masson SAS}}, series = {{Anaesthesia Critical Care & Pain Medicine}}, title = {{Update in antibiotic therapy in intensive care unit : report from the 2019 Nîmes International Symposium}}, url = {{http://dx.doi.org/10.1016/j.accpm.2019.09.009}}, doi = {{10.1016/j.accpm.2019.09.009}}, volume = {{38}}, year = {{2019}}, }