Conversion of 2-(trimethylsilyl)ethyl sulfides into thioesters
(1999) In Tetrahedron Letters 40(9). p.1811-1814- Abstract
Treatment of 2-(trimethylsilyl)ethyl sulfides with a carboxylic acid chloride and AgBF4 in CH2Cl2 furnishes the corresponding thioesters in high yields and purities. The conversion of 2-(trimethylsilyl)ethyl sulfides into synthetically versatile thioesters allows such sulfides to be used as sulfhydryl protective groups, since such sulfides are easily prepared and are stable towards many reaction conditions encountered in organic syntheses.
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https://lup.lub.lu.se/record/91f73866-7f4e-49ea-80af-22e9472d9f8f
- author
- Grundberg, Hans LU ; Andergran, Magnus and Nilsson, Ulf J. LU
- organization
- publishing date
- 1999-02-26
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Tetrahedron Letters
- volume
- 40
- issue
- 9
- pages
- 4 pages
- publisher
- Elsevier
- external identifiers
-
- scopus:0033605182
- ISSN
- 0040-4039
- DOI
- 10.1016/S0040-4039(99)00016-7
- language
- English
- LU publication?
- yes
- id
- 91f73866-7f4e-49ea-80af-22e9472d9f8f
- date added to LUP
- 2023-02-07 08:57:17
- date last changed
- 2023-02-21 10:30:13
@article{91f73866-7f4e-49ea-80af-22e9472d9f8f, abstract = {{<p>Treatment of 2-(trimethylsilyl)ethyl sulfides with a carboxylic acid chloride and AgBF<sub>4</sub> in CH<sub>2</sub>Cl<sub>2</sub> furnishes the corresponding thioesters in high yields and purities. The conversion of 2-(trimethylsilyl)ethyl sulfides into synthetically versatile thioesters allows such sulfides to be used as sulfhydryl protective groups, since such sulfides are easily prepared and are stable towards many reaction conditions encountered in organic syntheses.</p>}}, author = {{Grundberg, Hans and Andergran, Magnus and Nilsson, Ulf J.}}, issn = {{0040-4039}}, language = {{eng}}, month = {{02}}, number = {{9}}, pages = {{1811--1814}}, publisher = {{Elsevier}}, series = {{Tetrahedron Letters}}, title = {{Conversion of 2-(trimethylsilyl)ethyl sulfides into thioesters}}, url = {{http://dx.doi.org/10.1016/S0040-4039(99)00016-7}}, doi = {{10.1016/S0040-4039(99)00016-7}}, volume = {{40}}, year = {{1999}}, }