No strong relationship between body mass index and clinical hand osteoarthritis : results from a population-based case-control study
(2014) In Scandinavian Journal of Rheumatology 43(5). p.15-409- Abstract
OBJECTIVES: The aim of this population-based case-control study was to investigate whether a high body mass index (BMI) is a risk factor for clinical hand osteoarthritis (OA).
METHOD: Persons living in Ullensaker municipality in Norway who were aged 20-52 years in 1990 reported height and weight in 1990, 1994, 2004, and 2010 (n = 1276). Cases (clinical hand OA in 2010, n = 59) were compared to controls (participants without self-reported OA or hand pain in 2010, n = 805) with regard to the prospectively measured BMI by means of a generalized estimating equation (GEE) analysis adjusted for age, sex, time, and education.
RESULTS: The mean age of hand OA cases was 64 (SD = 7.5) years in 2010 and 78% were women. There was no... (More)
OBJECTIVES: The aim of this population-based case-control study was to investigate whether a high body mass index (BMI) is a risk factor for clinical hand osteoarthritis (OA).
METHOD: Persons living in Ullensaker municipality in Norway who were aged 20-52 years in 1990 reported height and weight in 1990, 1994, 2004, and 2010 (n = 1276). Cases (clinical hand OA in 2010, n = 59) were compared to controls (participants without self-reported OA or hand pain in 2010, n = 805) with regard to the prospectively measured BMI by means of a generalized estimating equation (GEE) analysis adjusted for age, sex, time, and education.
RESULTS: The mean age of hand OA cases was 64 (SD = 7.5) years in 2010 and 78% were women. There was no association between total average BMI over the entire period and later clinical hand OA (p = 0.320). Cases had a higher mean BMI in 1990 [unstandardized B = 0.93, 95% confidence interval (CI) 0.07-1.79] and in 1994 (B = 0.75, 95% CI 0.22-1.28) but there were no differences between the groups in 2004 or 2010.
CONCLUSIONS: The study lend support to the hypothesis that having a higher BMI when young or middle-aged might be associated with later hand OA.
(Less)
- author
- Magnusson, K LU ; Østerås, N ; Haugen, I K ; Mowinckel, P ; Nordsletten, L ; Natvig, B and Hagen, K B
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Adult, Age Factors, Aged, Body Mass Index, Case-Control Studies, Female, Hand Joints/physiopathology, Humans, Longitudinal Studies, Male, Middle Aged, Models, Statistical, Norway, Obesity/complications, Osteoarthritis/epidemiology, Prospective Studies, Retrospective Studies, Risk Factors, Surveys and Questionnaires
- in
- Scandinavian Journal of Rheumatology
- volume
- 43
- issue
- 5
- pages
- 7 pages
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:24824945
- scopus:84921814382
- ISSN
- 1502-7732
- DOI
- 10.3109/03009742.2014.900700
- language
- English
- LU publication?
- no
- id
- 91f9dfbd-0097-4e36-87f8-7f62ac04988b
- date added to LUP
- 2018-11-29 15:12:36
- date last changed
- 2024-03-18 20:16:06
@article{91f9dfbd-0097-4e36-87f8-7f62ac04988b,
abstract = {{<p>OBJECTIVES: The aim of this population-based case-control study was to investigate whether a high body mass index (BMI) is a risk factor for clinical hand osteoarthritis (OA).</p><p>METHOD: Persons living in Ullensaker municipality in Norway who were aged 20-52 years in 1990 reported height and weight in 1990, 1994, 2004, and 2010 (n = 1276). Cases (clinical hand OA in 2010, n = 59) were compared to controls (participants without self-reported OA or hand pain in 2010, n = 805) with regard to the prospectively measured BMI by means of a generalized estimating equation (GEE) analysis adjusted for age, sex, time, and education.</p><p>RESULTS: The mean age of hand OA cases was 64 (SD = 7.5) years in 2010 and 78% were women. There was no association between total average BMI over the entire period and later clinical hand OA (p = 0.320). Cases had a higher mean BMI in 1990 [unstandardized B = 0.93, 95% confidence interval (CI) 0.07-1.79] and in 1994 (B = 0.75, 95% CI 0.22-1.28) but there were no differences between the groups in 2004 or 2010.</p><p>CONCLUSIONS: The study lend support to the hypothesis that having a higher BMI when young or middle-aged might be associated with later hand OA.</p>}},
author = {{Magnusson, K and Østerås, N and Haugen, I K and Mowinckel, P and Nordsletten, L and Natvig, B and Hagen, K B}},
issn = {{1502-7732}},
keywords = {{Adult; Age Factors; Aged; Body Mass Index; Case-Control Studies; Female; Hand Joints/physiopathology; Humans; Longitudinal Studies; Male; Middle Aged; Models, Statistical; Norway; Obesity/complications; Osteoarthritis/epidemiology; Prospective Studies; Retrospective Studies; Risk Factors; Surveys and Questionnaires}},
language = {{eng}},
number = {{5}},
pages = {{15--409}},
publisher = {{Taylor & Francis}},
series = {{Scandinavian Journal of Rheumatology}},
title = {{No strong relationship between body mass index and clinical hand osteoarthritis : results from a population-based case-control study}},
url = {{http://dx.doi.org/10.3109/03009742.2014.900700}},
doi = {{10.3109/03009742.2014.900700}},
volume = {{43}},
year = {{2014}},
}