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Optic disc diameter influences the ability to detect glaucomatous disc damage

Heijl, A LU and Mölder, H (1993) In Acta Ophthalmologica 71(1). p.9-122
Abstract

We studied the influence of optic disc diameter on the diagnostic power of subjective disc evaluation of glaucoma. One hundred and thirteen colour disc photographs of 91 patients with primary open angle glaucoma and 174 photographs of 89 randomly selected normal subjects were studied. Five ophthalmologists independently classified all eyes as glaucomatous or normal by disc appearance using a masked forced choice design. Sensitivities and specificities varied strongly as a function of disc diameter. Overall sensitivity for recognizing glaucoma by disc inspection was 58% in small discs, 72% in the middle group and 85% in the group of large discs. These differences were significant, and the odds of recognizing a glaucomatous disc as such... (More)

We studied the influence of optic disc diameter on the diagnostic power of subjective disc evaluation of glaucoma. One hundred and thirteen colour disc photographs of 91 patients with primary open angle glaucoma and 174 photographs of 89 randomly selected normal subjects were studied. Five ophthalmologists independently classified all eyes as glaucomatous or normal by disc appearance using a masked forced choice design. Sensitivities and specificities varied strongly as a function of disc diameter. Overall sensitivity for recognizing glaucoma by disc inspection was 58% in small discs, 72% in the middle group and 85% in the group of large discs. These differences were significant, and the odds of recognizing a glaucomatous disc as such increased by a factor of 2.07 between each group. Overall specificity was 99.6% in small discs, 95% in the middle group, and 79% in large normal discs. Thus, larger discs were more likely to be classified as glaucomatous whether they were glaucomatous or not, while small discs were more likely to be classified as normal.

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publication status
published
subject
keywords
Adult, Aged, Aged, 80 and over, Fundus Oculi, Glaucoma, Open-Angle/pathology, Humans, Image Processing, Computer-Assisted, Middle Aged, Optic Disk/pathology, Optic Nerve/pathology, Photography, Random Allocation, Reproducibility of Results, Sensitivity and Specificity
in
Acta Ophthalmologica
volume
71
issue
1
pages
8 pages
publisher
Wiley-Blackwell
external identifiers
  • scopus:0027474018
  • pmid:8475706
ISSN
0001-639X
language
English
LU publication?
yes
id
92d32ae6-3e78-4651-a1b4-9cefd9c8fac5
date added to LUP
2019-06-30 16:10:08
date last changed
2024-04-02 11:39:41
@article{92d32ae6-3e78-4651-a1b4-9cefd9c8fac5,
  abstract     = {{<p>We studied the influence of optic disc diameter on the diagnostic power of subjective disc evaluation of glaucoma. One hundred and thirteen colour disc photographs of 91 patients with primary open angle glaucoma and 174 photographs of 89 randomly selected normal subjects were studied. Five ophthalmologists independently classified all eyes as glaucomatous or normal by disc appearance using a masked forced choice design. Sensitivities and specificities varied strongly as a function of disc diameter. Overall sensitivity for recognizing glaucoma by disc inspection was 58% in small discs, 72% in the middle group and 85% in the group of large discs. These differences were significant, and the odds of recognizing a glaucomatous disc as such increased by a factor of 2.07 between each group. Overall specificity was 99.6% in small discs, 95% in the middle group, and 79% in large normal discs. Thus, larger discs were more likely to be classified as glaucomatous whether they were glaucomatous or not, while small discs were more likely to be classified as normal.</p>}},
  author       = {{Heijl, A and Mölder, H}},
  issn         = {{0001-639X}},
  keywords     = {{Adult; Aged; Aged, 80 and over; Fundus Oculi; Glaucoma, Open-Angle/pathology; Humans; Image Processing, Computer-Assisted; Middle Aged; Optic Disk/pathology; Optic Nerve/pathology; Photography; Random Allocation; Reproducibility of Results; Sensitivity and Specificity}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{9--122}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Ophthalmologica}},
  title        = {{Optic disc diameter influences the ability to detect glaucomatous disc damage}},
  volume       = {{71}},
  year         = {{1993}},
}