Erectile and Clitoral Dysfunction as Harbingers of Cardiovascular Disease : A Perspective
(2026) In Medicina (Lithuania) 62(2).- Abstract
Sexual dysfunction (SD), more specifically vasculogenic erectile dysfunction (ED) in men and female sexual arousal disorder (FSAD) in women, is increasingly recognized as a marker of cardiovascular disease (CVD). While extensive literature documents vasculogenic ED as an early warning sign of coronary artery disease (CAD) and other atherosclerotic manifestations, the evidence for analogous phenomena in women is emerging but less mature. This perspective explores epidemiologic associations, shared pathophysiologic mechanisms, clinical implications, and screening paradigms for ED and FSAD as cardiovascular (CV) risk-enhancing conditions. This perspective endorses that clinicians should incorporate genital vasculogenic SD into CV risk... (More)
Sexual dysfunction (SD), more specifically vasculogenic erectile dysfunction (ED) in men and female sexual arousal disorder (FSAD) in women, is increasingly recognized as a marker of cardiovascular disease (CVD). While extensive literature documents vasculogenic ED as an early warning sign of coronary artery disease (CAD) and other atherosclerotic manifestations, the evidence for analogous phenomena in women is emerging but less mature. This perspective explores epidemiologic associations, shared pathophysiologic mechanisms, clinical implications, and screening paradigms for ED and FSAD as cardiovascular (CV) risk-enhancing conditions. This perspective endorses that clinicians should incorporate genital vasculogenic SD into CV risk stratification and that multidisciplinary care (primary care, cardiology, urology/gynecology) is warranted. A summary table outlines key features and actionable steps.
(Less)
- author
- Priviero, Fernanda
; Hollis, Fiona
; Wood, Susan K.
; Uline, Mark
; Andersson, Karl Erik
LU
and Webb, R. Clinton
- organization
- publishing date
- 2026-02
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- clitoris, erectile dysfunction, female sexual arousal disorder, female sexual dysfunction, penis, sexual dysfunction
- in
- Medicina (Lithuania)
- volume
- 62
- issue
- 2
- article number
- 416
- publisher
- MDPI AG
- external identifiers
-
- scopus:105031418966
- pmid:41752814
- ISSN
- 1010-660X
- DOI
- 10.3390/medicina62020416
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2026 by the authors.
- id
- 93646b39-0a46-4ce2-8e17-faa2f8b6a65c
- date added to LUP
- 2026-04-08 15:58:48
- date last changed
- 2026-06-03 21:34:47
@article{93646b39-0a46-4ce2-8e17-faa2f8b6a65c,
abstract = {{<p>Sexual dysfunction (SD), more specifically vasculogenic erectile dysfunction (ED) in men and female sexual arousal disorder (FSAD) in women, is increasingly recognized as a marker of cardiovascular disease (CVD). While extensive literature documents vasculogenic ED as an early warning sign of coronary artery disease (CAD) and other atherosclerotic manifestations, the evidence for analogous phenomena in women is emerging but less mature. This perspective explores epidemiologic associations, shared pathophysiologic mechanisms, clinical implications, and screening paradigms for ED and FSAD as cardiovascular (CV) risk-enhancing conditions. This perspective endorses that clinicians should incorporate genital vasculogenic SD into CV risk stratification and that multidisciplinary care (primary care, cardiology, urology/gynecology) is warranted. A summary table outlines key features and actionable steps.</p>}},
author = {{Priviero, Fernanda and Hollis, Fiona and Wood, Susan K. and Uline, Mark and Andersson, Karl Erik and Webb, R. Clinton}},
issn = {{1010-660X}},
keywords = {{clitoris; erectile dysfunction; female sexual arousal disorder; female sexual dysfunction; penis; sexual dysfunction}},
language = {{eng}},
number = {{2}},
publisher = {{MDPI AG}},
series = {{Medicina (Lithuania)}},
title = {{Erectile and Clitoral Dysfunction as Harbingers of Cardiovascular Disease : A Perspective}},
url = {{http://dx.doi.org/10.3390/medicina62020416}},
doi = {{10.3390/medicina62020416}},
volume = {{62}},
year = {{2026}},
}