In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions. II: Discriminant analysis between nevus and melanoma
(1992) In Photochemistry and Photobiology 55(4). p.515-522- Abstract
- Reflectance spectrophotometry from 420 to 780 nm on 31 primary melanoma and 31 benign nevi has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of melanoma and nevi manifest dissimilar patterns. From these spectra four variables, whose physical and/or physiological meanings remain to be investigated, have been derived. All of them are significantly different when compared between melanoma and nevi. A discriminant function between the two groups of lesions has been determined by using a stepwise discriminant analysis, resulting in a test with a sensitivity of 90.3% and a specificity of 77.4%. This method of discrimination between melanoma and nevi seems to have... (More)
- Reflectance spectrophotometry from 420 to 780 nm on 31 primary melanoma and 31 benign nevi has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of melanoma and nevi manifest dissimilar patterns. From these spectra four variables, whose physical and/or physiological meanings remain to be investigated, have been derived. All of them are significantly different when compared between melanoma and nevi. A discriminant function between the two groups of lesions has been determined by using a stepwise discriminant analysis, resulting in a test with a sensitivity of 90.3% and a specificity of 77.4%. This method of discrimination between melanoma and nevi seems to have a discriminating power almost equal to that of a clinical judgement from a specialized medical doctor, thus suggesting a new method for screening skin pigmented lesions. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1106462
- author
- Marchesini, R ; Cascinelli, N ; Brambilla, M ; Clemente, C ; Mascheroni, L ; Pignoli, E ; Testori, A and Venturoli, Daniele LU
- publishing date
- 1992
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Photochemistry and Photobiology
- volume
- 55
- issue
- 4
- pages
- 515 - 522
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:1620728
- scopus:0026842788
- ISSN
- 0031-8655
- DOI
- 10.1111/j.1751-1097.1992.tb04272.x
- language
- English
- LU publication?
- no
- id
- 937ca93e-11e2-4d2d-88c3-774d780b7cba (old id 1106462)
- date added to LUP
- 2016-04-01 12:30:26
- date last changed
- 2025-10-14 13:00:15
@article{937ca93e-11e2-4d2d-88c3-774d780b7cba,
abstract = {{Reflectance spectrophotometry from 420 to 780 nm on 31 primary melanoma and 31 benign nevi has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of melanoma and nevi manifest dissimilar patterns. From these spectra four variables, whose physical and/or physiological meanings remain to be investigated, have been derived. All of them are significantly different when compared between melanoma and nevi. A discriminant function between the two groups of lesions has been determined by using a stepwise discriminant analysis, resulting in a test with a sensitivity of 90.3% and a specificity of 77.4%. This method of discrimination between melanoma and nevi seems to have a discriminating power almost equal to that of a clinical judgement from a specialized medical doctor, thus suggesting a new method for screening skin pigmented lesions.}},
author = {{Marchesini, R and Cascinelli, N and Brambilla, M and Clemente, C and Mascheroni, L and Pignoli, E and Testori, A and Venturoli, Daniele}},
issn = {{0031-8655}},
language = {{eng}},
number = {{4}},
pages = {{515--522}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Photochemistry and Photobiology}},
title = {{In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions. II: Discriminant analysis between nevus and melanoma}},
url = {{http://dx.doi.org/10.1111/j.1751-1097.1992.tb04272.x}},
doi = {{10.1111/j.1751-1097.1992.tb04272.x}},
volume = {{55}},
year = {{1992}},
}