Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Accuracy of MRI in early rectal cancer: national cohort study

Rosén, Roberto LU orcid ; Nilsson, Emelie LU ; Rahman, Milladur LU orcid and Rönnow, Carl-Fredrik LU (2022) In The British journal of surgery
Abstract
Radiological staging of rectal cancer dictates subsequent patient
treatment. In early-stage disease, local excision is associated
with reduced morbidity, mortality, and costs, and maintains
bowel continuity compared with surgery, where the whole or
part of the rectum is resected1–3
. Nearly 90 per cent of patients
with T1 rectal cancer have N0 disease and are therefore potentially curable with local resection, yet the majority undergo major resection4–6
. MRI is the primary staging investigation used to predict
local stage in rectal cancer7, mainly owing to its ability to allocate
patients in need of neoadjuvant treatment8–10. There is potentially inaccuracy in MRI staging for nodal involvement and... (More)
Radiological staging of rectal cancer dictates subsequent patient
treatment. In early-stage disease, local excision is associated
with reduced morbidity, mortality, and costs, and maintains
bowel continuity compared with surgery, where the whole or
part of the rectum is resected1–3
. Nearly 90 per cent of patients
with T1 rectal cancer have N0 disease and are therefore potentially curable with local resection, yet the majority undergo major resection4–6
. MRI is the primary staging investigation used to predict
local stage in rectal cancer7, mainly owing to its ability to allocate
patients in need of neoadjuvant treatment8–10. There is potentially inaccuracy in MRI staging for nodal involvement and differentiation of T1 from T2 tumours6,7,11. Consequently, cT1 and cT2 are
often combined and comprice tumours considered for local resection. Apart from a recent study6 reporting 54 per cent accuracy for
MRI cT1–2 category, combined cT1–2 status has not been
investigated.
The aim of this large nationwide retrospective cohort study was
to investigate the staging accuracy of MRI, from a clinical perspective, in early rectal cancer when combining cT1 and cT2 categories.
(Less)
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
The British journal of surgery
article number
znac059
publisher
Oxford University Press
external identifiers
  • scopus:85132050052
  • pmid:35277966
ISSN
1365-2168
DOI
10.1093/bjs/znac059
project
Challenges of early rectal cancer
language
English
LU publication?
yes
id
938d826b-05d5-454c-983b-85c4f7927d96
date added to LUP
2022-03-31 14:50:54
date last changed
2025-04-18 22:53:42
@article{938d826b-05d5-454c-983b-85c4f7927d96,
  abstract     = {{Radiological staging of rectal cancer dictates subsequent patient<br/>treatment. In early-stage disease, local excision is associated<br/>with reduced morbidity, mortality, and costs, and maintains<br/>bowel continuity compared with surgery, where the whole or<br/>part of the rectum is resected1–3<br/>. Nearly 90 per cent of patients<br/>with T1 rectal cancer have N0 disease and are therefore potentially curable with local resection, yet the majority undergo major resection4–6<br/>. MRI is the primary staging investigation used to predict<br/>local stage in rectal cancer7, mainly owing to its ability to allocate<br/>patients in need of neoadjuvant treatment8–10. There is potentially inaccuracy in MRI staging for nodal involvement and differentiation of T1 from T2 tumours6,7,11. Consequently, cT1 and cT2 are<br/>often combined and comprice tumours considered for local resection. Apart from a recent study6 reporting 54 per cent accuracy for<br/>MRI cT1–2 category, combined cT1–2 status has not been<br/>investigated.<br/>The aim of this large nationwide retrospective cohort study was<br/>to investigate the staging accuracy of MRI, from a clinical perspective, in early rectal cancer when combining cT1 and cT2 categories.<br/>}},
  author       = {{Rosén, Roberto and Nilsson, Emelie and Rahman, Milladur and Rönnow, Carl-Fredrik}},
  issn         = {{1365-2168}},
  language     = {{eng}},
  month        = {{03}},
  publisher    = {{Oxford University Press}},
  series       = {{The British journal of surgery}},
  title        = {{Accuracy of MRI in early rectal cancer: national cohort study}},
  url          = {{http://dx.doi.org/10.1093/bjs/znac059}},
  doi          = {{10.1093/bjs/znac059}},
  year         = {{2022}},
}