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Revisiting guidelines for integration of flow cytometry results in the WHO classification of myelodysplastic syndromes - Proposal from the International/European LeukemiaNet Working Group for Flow Cytometry in MDS

Porwit, A. LU ; Van De Loosdrecht, A. A. ; Bettelheim, P. ; Eidenschink Brodersen, L. ; Burbury, K. ; Cremers, E. ; Della Porta, M. G. ; Ireland, R. ; Johansson, U. and Matarraz, S. , et al. (2014) In Leukemia 28(9). p.1793-1798
Abstract

Definite progress has been made in the exploration of myelodysplastic syndromes (MDS) by flow cytometry (FCM) since the publication of the World Health Organization 2008 classification of myeloid neoplasms. An international working party initiated within the European LeukemiaNet and extended to include members from Australia, Canada, Japan, Taiwan and the United States has, through several workshops, developed and subsequently published consensus recommendations. The latter deal with preanalytical precautions, and propose small and large panels, which allow evaluating immunophenotypic anomalies and calculating myelodysplasia scores. The current paper provides guidelines that strongly recommend the integration of FCM data with other... (More)

Definite progress has been made in the exploration of myelodysplastic syndromes (MDS) by flow cytometry (FCM) since the publication of the World Health Organization 2008 classification of myeloid neoplasms. An international working party initiated within the European LeukemiaNet and extended to include members from Australia, Canada, Japan, Taiwan and the United States has, through several workshops, developed and subsequently published consensus recommendations. The latter deal with preanalytical precautions, and propose small and large panels, which allow evaluating immunophenotypic anomalies and calculating myelodysplasia scores. The current paper provides guidelines that strongly recommend the integration of FCM data with other diagnostic tools in the diagnostic work-up of MDS.

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publishing date
type
Contribution to journal
publication status
published
in
Leukemia
volume
28
issue
9
pages
6 pages
publisher
Nature Publishing Group
external identifiers
  • scopus:84908307908
  • pmid:24919805
ISSN
0887-6924
DOI
10.1038/leu.2014.191
language
English
LU publication?
no
id
93f9e791-06be-4731-a313-b14dbb085dc0
date added to LUP
2019-05-22 09:47:57
date last changed
2024-01-15 21:10:10
@article{93f9e791-06be-4731-a313-b14dbb085dc0,
  abstract     = {{<p>Definite progress has been made in the exploration of myelodysplastic syndromes (MDS) by flow cytometry (FCM) since the publication of the World Health Organization 2008 classification of myeloid neoplasms. An international working party initiated within the European LeukemiaNet and extended to include members from Australia, Canada, Japan, Taiwan and the United States has, through several workshops, developed and subsequently published consensus recommendations. The latter deal with preanalytical precautions, and propose small and large panels, which allow evaluating immunophenotypic anomalies and calculating myelodysplasia scores. The current paper provides guidelines that strongly recommend the integration of FCM data with other diagnostic tools in the diagnostic work-up of MDS.</p>}},
  author       = {{Porwit, A. and Van De Loosdrecht, A. A. and Bettelheim, P. and Eidenschink Brodersen, L. and Burbury, K. and Cremers, E. and Della Porta, M. G. and Ireland, R. and Johansson, U. and Matarraz, S. and Ogata, K. and Orfao, A. and Preijers, F. and Psarra, K. and Subirá, D. and Valent, P. and Van Der Velden, V. H.J. and Wells, D. and Westers, T. M. and Kern, W. and Béné, M. C.}},
  issn         = {{0887-6924}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{9}},
  pages        = {{1793--1798}},
  publisher    = {{Nature Publishing Group}},
  series       = {{Leukemia}},
  title        = {{Revisiting guidelines for integration of flow cytometry results in the WHO classification of myelodysplastic syndromes - Proposal from the International/European LeukemiaNet Working Group for Flow Cytometry in MDS}},
  url          = {{http://dx.doi.org/10.1038/leu.2014.191}},
  doi          = {{10.1038/leu.2014.191}},
  volume       = {{28}},
  year         = {{2014}},
}