Patients’ symptoms and challenges during the first year after allogeneic haematopoietic cell transplantation—patients’ own expressions
Hagelin, Carina Lundh LU ; Kisch, Annika M. LU
; Holmberg, Katarina
; O’Sullivan, Anna
; Wengström, Yvonne
; Winterling, Jeanette
LU
and Bergkvist, Karin
(2026)
In Supportive Care in Cancer
34(5).
- Abstract
Purpose: The study aimed to describe patients’ experiences of physical, psychological, social, and existential symptoms and challenges during the first year after allogeneic haematopoietic cell transplantation (allo-HCT). Methods: Quantitative and qualitative data were collected and analysed with descriptive methods as part of a large retrospective cross-sectional online survey of patients who underwent allo-HCT between 2017 and 2020. Results: In total, 126 (59.7%) of all eligible patients participated, mean age 57 years (range 21–75), equal distribution of gender and time after allo-HCT. Most patients (58%) had experienced fewer than 5 coexisting symptoms, although 8% reported more than 10. Physical symptoms or challenges (83.0%) were... (More)
Purpose: The study aimed to describe patients’ experiences of physical, psychological, social, and existential symptoms and challenges during the first year after allogeneic haematopoietic cell transplantation (allo-HCT). Methods: Quantitative and qualitative data were collected and analysed with descriptive methods as part of a large retrospective cross-sectional online survey of patients who underwent allo-HCT between 2017 and 2020. Results: In total, 126 (59.7%) of all eligible patients participated, mean age 57 years (range 21–75), equal distribution of gender and time after allo-HCT. Most patients (58%) had experienced fewer than 5 coexisting symptoms, although 8% reported more than 10. Physical symptoms or challenges (83.0%) were most often reported, followed by social (52%), existential (50%), and psychological (43%), as described in responses to open-ended questions. Analysed descriptions resulted in 12 categories/areas of physical symptoms and challenges; two categories each of psychological—My inner self and Me in my context; social—Social isolation and Impact on relationships; and existential symptoms and challenges—Re-evaluating life and myself and An uncertain future. Conclusion: Patients experienced a variety of symptoms and challenges as a multidimensional experience during the first year after allo-HCT. A holistic approach to symptoms and challenges is needed to address individual patients’ situations. This knowledge emphasises the importance of patients receiving supportive care to navigate life after transplantation and into survivorship.
(Less)
- author
- Hagelin, Carina Lundh
LU
; Kisch, Annika M.
LU
; Holmberg, Katarina
; O’Sullivan, Anna
; Wengström, Yvonne
; Winterling, Jeanette
LU
and Bergkvist, Karin
- organization
- publishing date
- 2026-05
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Allogeneic haematopoietic cell transplantation, Cancer, Cancer survivorship, Multidimensional challenge, Symptom experiences, Symptom occurrence
- in
- Supportive Care in Cancer
- volume
- 34
- issue
- 5
- article number
- 429
- publisher
- Springer Science and Business Media B.V.
- external identifiers
-
- scopus:105035820781
- pmid:41986694
- ISSN
- 0941-4355
- DOI
- 10.1007/s00520-026-10655-5
- language
- English
- LU publication?
- yes
- id
- 944fff73-f113-4196-9ccb-18584b61cf31
- date added to LUP
- 2026-05-29 11:44:04
- date last changed
- 2026-06-12 13:14:37
@article{944fff73-f113-4196-9ccb-18584b61cf31,
abstract = {{<p>Purpose: The study aimed to describe patients’ experiences of physical, psychological, social, and existential symptoms and challenges during the first year after allogeneic haematopoietic cell transplantation (allo-HCT). Methods: Quantitative and qualitative data were collected and analysed with descriptive methods as part of a large retrospective cross-sectional online survey of patients who underwent allo-HCT between 2017 and 2020. Results: In total, 126 (59.7%) of all eligible patients participated, mean age 57 years (range 21–75), equal distribution of gender and time after allo-HCT. Most patients (58%) had experienced fewer than 5 coexisting symptoms, although 8% reported more than 10. Physical symptoms or challenges (83.0%) were most often reported, followed by social (52%), existential (50%), and psychological (43%), as described in responses to open-ended questions. Analysed descriptions resulted in 12 categories/areas of physical symptoms and challenges; two categories each of psychological—My inner self and Me in my context; social—Social isolation and Impact on relationships; and existential symptoms and challenges—Re-evaluating life and myself and An uncertain future. Conclusion: Patients experienced a variety of symptoms and challenges as a multidimensional experience during the first year after allo-HCT. A holistic approach to symptoms and challenges is needed to address individual patients’ situations. This knowledge emphasises the importance of patients receiving supportive care to navigate life after transplantation and into survivorship.</p>}},
author = {{Hagelin, Carina Lundh and Kisch, Annika M. and Holmberg, Katarina and O’Sullivan, Anna and Wengström, Yvonne and Winterling, Jeanette and Bergkvist, Karin}},
issn = {{0941-4355}},
keywords = {{Allogeneic haematopoietic cell transplantation; Cancer; Cancer survivorship; Multidimensional challenge; Symptom experiences; Symptom occurrence}},
language = {{eng}},
number = {{5}},
publisher = {{Springer Science and Business Media B.V.}},
series = {{Supportive Care in Cancer}},
title = {{Patients’ symptoms and challenges during the first year after allogeneic haematopoietic cell transplantation—patients’ own expressions}},
url = {{http://dx.doi.org/10.1007/s00520-026-10655-5}},
doi = {{10.1007/s00520-026-10655-5}},
volume = {{34}},
year = {{2026}},
}