Congenital heart disease : changes in recorded birth prevalence and cardiac interventions over the past half-century in Sweden
(2023) In European Journal of Preventive Cardiology 30(2). p.169-176- Abstract
Aims Our objective was to assess changes in the birth prevalence of CHD over a half-century in a high-resource, nationwide setting, as well as changes in the prevalence of cardiac interventions in this population. Methods The Swedish National Patient and Cause of Death registers were linked to estimate the annual rates of CHD and cardiac and results interventions among live-born infants from 1970 to 2017. Additionally, separate estimates were obtained by lesion complexity, from mild to the most complex forms of CHD. Overall, the numbers of live-born infants with a CHD identified varied from 624 to 2459 annual cases, with rates increasing steadily from 5.7 to an average of 20 per 1000 live births at the end of the study period, and with... (More)
Aims Our objective was to assess changes in the birth prevalence of CHD over a half-century in a high-resource, nationwide setting, as well as changes in the prevalence of cardiac interventions in this population. Methods The Swedish National Patient and Cause of Death registers were linked to estimate the annual rates of CHD and cardiac and results interventions among live-born infants from 1970 to 2017. Additionally, separate estimates were obtained by lesion complexity, from mild to the most complex forms of CHD. Overall, the numbers of live-born infants with a CHD identified varied from 624 to 2459 annual cases, with rates increasing steadily from 5.7 to an average of 20 per 1000 live births at the end of the study period, and with a more pronounced increase from 1996 to 2005. The largest increase over time was observed for mild CHD lesions. Overall, the proportion of cardiac interventions among patients with CHD declined from 40.7% in 1970 to below 15.0% after 2014. However, in the most complex CHD lesion groups, overall cardiac interventions increased from 57.1 to 76.8% in patients with conotruncal defects and from 32.8 to 39.5% in those with severe non-conotruncal defects. Conclusion The live-birth prevalence of CHD in Sweden more than tripled during the past half-century, most likely resulting from more accurate diagnostic capabilities. The largest increase over time was observed among patients with simple defects. During the same period, overall cardiac interventions decreased whereas interventions for the most complex CHD groups increased.
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- author
- Giang, Kok Wai ; Mandalenakis, Zacharias ; Fedchenko, Maria ; Eriksson, Peter ; Rosengren, Annika ; Norman, Mikael ; Hanséus, Katarina LU and Dellborg, Mikael
- organization
- publishing date
- 2023-02
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Congenital heart disease, Epidemiology, Prevalence, Temporal trends
- in
- European Journal of Preventive Cardiology
- volume
- 30
- issue
- 2
- pages
- 8 pages
- publisher
- Oxford University Press
- external identifiers
-
- pmid:36198066
- scopus:85180267476
- ISSN
- 2047-4873
- DOI
- 10.1093/eurjpc/zwac227
- language
- English
- LU publication?
- yes
- id
- 948e85c0-1c7f-4bf2-8fbc-d78840a35e79
- date added to LUP
- 2024-01-08 14:40:51
- date last changed
- 2024-04-23 10:16:20
@article{948e85c0-1c7f-4bf2-8fbc-d78840a35e79,
abstract = {{<p>Aims Our objective was to assess changes in the birth prevalence of CHD over a half-century in a high-resource, nationwide setting, as well as changes in the prevalence of cardiac interventions in this population. Methods The Swedish National Patient and Cause of Death registers were linked to estimate the annual rates of CHD and cardiac and results interventions among live-born infants from 1970 to 2017. Additionally, separate estimates were obtained by lesion complexity, from mild to the most complex forms of CHD. Overall, the numbers of live-born infants with a CHD identified varied from 624 to 2459 annual cases, with rates increasing steadily from 5.7 to an average of 20 per 1000 live births at the end of the study period, and with a more pronounced increase from 1996 to 2005. The largest increase over time was observed for mild CHD lesions. Overall, the proportion of cardiac interventions among patients with CHD declined from 40.7% in 1970 to below 15.0% after 2014. However, in the most complex CHD lesion groups, overall cardiac interventions increased from 57.1 to 76.8% in patients with conotruncal defects and from 32.8 to 39.5% in those with severe non-conotruncal defects. Conclusion The live-birth prevalence of CHD in Sweden more than tripled during the past half-century, most likely resulting from more accurate diagnostic capabilities. The largest increase over time was observed among patients with simple defects. During the same period, overall cardiac interventions decreased whereas interventions for the most complex CHD groups increased.</p>}},
author = {{Giang, Kok Wai and Mandalenakis, Zacharias and Fedchenko, Maria and Eriksson, Peter and Rosengren, Annika and Norman, Mikael and Hanséus, Katarina and Dellborg, Mikael}},
issn = {{2047-4873}},
keywords = {{Congenital heart disease; Epidemiology; Prevalence; Temporal trends}},
language = {{eng}},
number = {{2}},
pages = {{169--176}},
publisher = {{Oxford University Press}},
series = {{European Journal of Preventive Cardiology}},
title = {{Congenital heart disease : changes in recorded birth prevalence and cardiac interventions over the past half-century in Sweden}},
url = {{http://dx.doi.org/10.1093/eurjpc/zwac227}},
doi = {{10.1093/eurjpc/zwac227}},
volume = {{30}},
year = {{2023}},
}