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Excellent long time survival for Swedish patients starting home-hemodialysis with and without subsequent renal transplantations.

Rydell Johnsén, Helena LU ; Krützen, Lena ; Simonsen, Ole LU ; Clyne, Naomi LU orcid and Segelmark, Mårten LU (2013) In Hemodialysis International 17(4). p.523-531
Abstract
Survival for patients on dialysis is poor. Earlier reports have indicated that home-hemodialysis is associated with improved survival but most of the studies are old and report only short-time survival. The characteristics of patient populations are often incompletely described. In this study, we report long-term survival for patients starting home-hemodialysis as first treatment and estimate the impact on survival of age, comorbidity, decade of start of home-hemodialysis, sex, primary renal disease and subsequent renal transplantation. One hundred twenty-eight patients starting home-hemodialysis as first renal replacement therapy 1971-1998 in Lund were included. Data were collected from patient files, the Swedish Renal Registry and... (More)
Survival for patients on dialysis is poor. Earlier reports have indicated that home-hemodialysis is associated with improved survival but most of the studies are old and report only short-time survival. The characteristics of patient populations are often incompletely described. In this study, we report long-term survival for patients starting home-hemodialysis as first treatment and estimate the impact on survival of age, comorbidity, decade of start of home-hemodialysis, sex, primary renal disease and subsequent renal transplantation. One hundred twenty-eight patients starting home-hemodialysis as first renal replacement therapy 1971-1998 in Lund were included. Data were collected from patient files, the Swedish Renal Registry and Swedish census. Survival analysis was made as intention-to-treat analysis (including survival after transplantation) and on-dialysis-treatment analysis with patients censored at the day of transplantation. Ten-, twenty- and thirty-year survival were 68%, 36% and 18%. Survival was significantly affected by comorbidity, age and what decade the patients started home-hemodialysis. For patients younger than 60 years and with no comorbidities, the corresponding figures were 75%, 47% and 23% and a subsequent renal transplantation did not significantly influence survival. Long-term survival for patients starting home-hemodialysis is good, and improves decade by decade. Survival is significantly affected by patient age and comorbidity, but the contribution of subsequent renal transplantation was not significant for younger patients without comorbidities. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Hemodialysis International
volume
17
issue
4
pages
523 - 531
publisher
Wiley-Blackwell
external identifiers
  • wos:000325137100009
  • pmid:23577698
  • scopus:84884949273
  • pmid:23577698
ISSN
1542-4758
DOI
10.1111/hdi.12046
language
English
LU publication?
yes
id
961575d0-b2e2-4e14-bbbf-9018f55f02b1 (old id 3733898)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23577698?dopt=Abstract
date added to LUP
2016-04-01 11:03:47
date last changed
2022-01-26 05:05:11
@article{961575d0-b2e2-4e14-bbbf-9018f55f02b1,
  abstract     = {{Survival for patients on dialysis is poor. Earlier reports have indicated that home-hemodialysis is associated with improved survival but most of the studies are old and report only short-time survival. The characteristics of patient populations are often incompletely described. In this study, we report long-term survival for patients starting home-hemodialysis as first treatment and estimate the impact on survival of age, comorbidity, decade of start of home-hemodialysis, sex, primary renal disease and subsequent renal transplantation. One hundred twenty-eight patients starting home-hemodialysis as first renal replacement therapy 1971-1998 in Lund were included. Data were collected from patient files, the Swedish Renal Registry and Swedish census. Survival analysis was made as intention-to-treat analysis (including survival after transplantation) and on-dialysis-treatment analysis with patients censored at the day of transplantation. Ten-, twenty- and thirty-year survival were 68%, 36% and 18%. Survival was significantly affected by comorbidity, age and what decade the patients started home-hemodialysis. For patients younger than 60 years and with no comorbidities, the corresponding figures were 75%, 47% and 23% and a subsequent renal transplantation did not significantly influence survival. Long-term survival for patients starting home-hemodialysis is good, and improves decade by decade. Survival is significantly affected by patient age and comorbidity, but the contribution of subsequent renal transplantation was not significant for younger patients without comorbidities.}},
  author       = {{Rydell Johnsén, Helena and Krützen, Lena and Simonsen, Ole and Clyne, Naomi and Segelmark, Mårten}},
  issn         = {{1542-4758}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{523--531}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Hemodialysis International}},
  title        = {{Excellent long time survival for Swedish patients starting home-hemodialysis with and without subsequent renal transplantations.}},
  url          = {{http://dx.doi.org/10.1111/hdi.12046}},
  doi          = {{10.1111/hdi.12046}},
  volume       = {{17}},
  year         = {{2013}},
}