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Monte Carlo simulations related to gas-based optical diagnosis of human sinusitis

Persson, Linda LU ; Kristensson, Elias; Simonsson, Lisa and Svanberg, Sune LU (2007) In Journal of Biomedical Optics 12(5).
Abstract
We investigate the feasibility of using diode laser gas spectroscopy for sinusitis diagnostics. We simulate light propagation using the Monte Carlo concept, as implemented by the Advanced Systems Analysis Program (ASAP (TM)) software. Simulations and experimental data are compared for a model based on two scattering bodies representing human tissue, with an air gap in-between representing the sinus cavity. Simulations are also performed to investigate the detection geometries used in the experiments, as well as the influence of the optical properties of the scattering bodies. Finally, we explore the possibility of performing imaging measurements of the sinuses. Results suggest that a diagnostic technique complementary to already existing... (More)
We investigate the feasibility of using diode laser gas spectroscopy for sinusitis diagnostics. We simulate light propagation using the Monte Carlo concept, as implemented by the Advanced Systems Analysis Program (ASAP (TM)) software. Simulations and experimental data are compared for a model based on two scattering bodies representing human tissue, with an air gap in-between representing the sinus cavity. Simulations are also performed to investigate the detection geometries used in the experiments, as well as the influence of the optical properties of the scattering bodies. Finally, we explore the possibility of performing imaging measurements of the sinuses. Results suggest that a diagnostic technique complementary to already existing ones could be developed. (C) 2007 Society of Photo-Optical Instrumentation Engineers. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
simulations, infrared spectroscopy, diode lasers, scattering, molecular, spectroscopy, medicine
in
Journal of Biomedical Optics
volume
12
issue
5
publisher
Published by SPIE--the International Society for Optical Engineering in cooperation with International Biomedical Optics Society
external identifiers
  • wos:000251549600033
  • scopus:38449109837
ISSN
1083-3668
DOI
10.1117/1.2777179
language
English
LU publication?
yes
id
392ecbff-b1e4-43f3-b42e-6a68d17c3655 (old id 965902)
date added to LUP
2008-01-30 08:03:02
date last changed
2017-08-06 03:44:32
@article{392ecbff-b1e4-43f3-b42e-6a68d17c3655,
  abstract     = {We investigate the feasibility of using diode laser gas spectroscopy for sinusitis diagnostics. We simulate light propagation using the Monte Carlo concept, as implemented by the Advanced Systems Analysis Program (ASAP (TM)) software. Simulations and experimental data are compared for a model based on two scattering bodies representing human tissue, with an air gap in-between representing the sinus cavity. Simulations are also performed to investigate the detection geometries used in the experiments, as well as the influence of the optical properties of the scattering bodies. Finally, we explore the possibility of performing imaging measurements of the sinuses. Results suggest that a diagnostic technique complementary to already existing ones could be developed. (C) 2007 Society of Photo-Optical Instrumentation Engineers.},
  author       = {Persson, Linda and Kristensson, Elias and Simonsson, Lisa and Svanberg, Sune},
  issn         = {1083-3668},
  keyword      = {simulations,infrared spectroscopy,diode lasers,scattering,molecular,spectroscopy,medicine},
  language     = {eng},
  number       = {5},
  publisher    = {Published by SPIE--the International Society for Optical Engineering in cooperation with International Biomedical Optics Society},
  series       = {Journal of Biomedical Optics},
  title        = {Monte Carlo simulations related to gas-based optical diagnosis of human sinusitis},
  url          = {http://dx.doi.org/10.1117/1.2777179},
  volume       = {12},
  year         = {2007},
}