The effect of total body microwave hyperthermia and hepatic artery ligation on liver tumors—an experimental study in rats
Carlsson, Goran ; Hafström, Larsolof ; Hugander, Anders ; Jönsson, Per‐Ebbe ‐E ; Bolmsjö, Magnus and Persson, Bertil LU
(1983)
In Journal of Surgical Oncology
22(1).
p.37-40
- Abstract
The effect of general microwave hyperthermia and hepatic artery ligation (HAL) was tested on Wistar rats with a transplanted N‐methyl‐N‐nitroso‐guanidine‐induced adenocarcinoma in the liver. Total body hyperthermia (41.5°C for 1 hour, three times during 24 hours) was given on the same day as HAL, and 1, 2, and 3 days after. HAL induced a slower tumor growth than untreated controls. No additive effect was registered when total body microwave hyperthermia was added to HAL. When hyperthermia was added 2 days after HAL, there was a transient decrease in tumor volume as in the HAL series. Total body microwave hyperthermia added 3 days after HAL induced a faster tumor growth than after HAL alone. When hyperthermia was added the same day and 1... (More)
The effect of general microwave hyperthermia and hepatic artery ligation (HAL) was tested on Wistar rats with a transplanted N‐methyl‐N‐nitroso‐guanidine‐induced adenocarcinoma in the liver. Total body hyperthermia (41.5°C for 1 hour, three times during 24 hours) was given on the same day as HAL, and 1, 2, and 3 days after. HAL induced a slower tumor growth than untreated controls. No additive effect was registered when total body microwave hyperthermia was added to HAL. When hyperthermia was added 2 days after HAL, there was a transient decrease in tumor volume as in the HAL series. Total body microwave hyperthermia added 3 days after HAL induced a faster tumor growth than after HAL alone. When hyperthermia was added the same day and 1 day after HAL, there was a 50% mortality.
(Less)
- author
- Carlsson, Goran
; Hafström, Larsolof
; Hugander, Anders
; Jönsson, Per‐Ebbe ‐E
; Bolmsjö, Magnus
and Persson, Bertil
LU
- organization
- publishing date
- 1983-01-01
- type
- Contribution to journal
- publication status
- published
- keywords
- hepatic artery ligation, hyperthermia, liver tumor, microwaves
- in
- Journal of Surgical Oncology
- volume
- 22
- issue
- 1
- pages
- 4 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:0020658114
- pmid:6823115
- ISSN
- 0022-4790
- DOI
- 10.1002/jso.2930220110
- language
- English
- LU publication?
- yes
- id
- 97050baa-b08e-4f57-a669-1452d9cdbd6b
- date added to LUP
- 2020-05-07 21:28:55
- date last changed
- 2024-01-02 10:56:27
@article{97050baa-b08e-4f57-a669-1452d9cdbd6b,
abstract = {{<p>The effect of general microwave hyperthermia and hepatic artery ligation (HAL) was tested on Wistar rats with a transplanted N‐methyl‐N‐nitroso‐guanidine‐induced adenocarcinoma in the liver. Total body hyperthermia (41.5°C for 1 hour, three times during 24 hours) was given on the same day as HAL, and 1, 2, and 3 days after. HAL induced a slower tumor growth than untreated controls. No additive effect was registered when total body microwave hyperthermia was added to HAL. When hyperthermia was added 2 days after HAL, there was a transient decrease in tumor volume as in the HAL series. Total body microwave hyperthermia added 3 days after HAL induced a faster tumor growth than after HAL alone. When hyperthermia was added the same day and 1 day after HAL, there was a 50% mortality.</p>}},
author = {{Carlsson, Goran and Hafström, Larsolof and Hugander, Anders and Jönsson, Per‐Ebbe ‐E and Bolmsjö, Magnus and Persson, Bertil}},
issn = {{0022-4790}},
keywords = {{hepatic artery ligation; hyperthermia; liver tumor; microwaves}},
language = {{eng}},
month = {{01}},
number = {{1}},
pages = {{37--40}},
publisher = {{Wiley-Blackwell}},
series = {{Journal of Surgical Oncology}},
title = {{The effect of total body microwave hyperthermia and hepatic artery ligation on liver tumors—an experimental study in rats}},
url = {{http://dx.doi.org/10.1002/jso.2930220110}},
doi = {{10.1002/jso.2930220110}},
volume = {{22}},
year = {{1983}},
}