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Progress in miniaturisation of proteon arrays - a step closer to high-density nanoarrays

Borrebaeck, Carl LU and Wingren, Christer LU (2007) In Drug Discovery Today 12(19-20). p.813-819
Abstract
Protein microarrays is a technology with great promise for high-throughput proteomics. Designing high-performance protein microarrays for global proteome analysis has, however, turned out to be challenging. To this end, major efforts are under way to design novel array formats capable of harboring the tremendous range of probes required to target complex proteomes composed of more than 10 000 analytes. By adopting nanotechnology, the first generation of miniaturized nanoarrays has recently emerged, which opens up new avenues for global proteome analysis and disease proteomics. This review describes the progress and key issues in designing miniaturized protein arrays.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Drug Discovery Today
volume
12
issue
19-20
pages
813 - 819
publisher
Elsevier
external identifiers
  • wos:000250661600004
  • scopus:35148869587
ISSN
1878-5832
DOI
10.1016/j.drudis.2007.08.003
language
English
LU publication?
yes
id
d0ddc32f-7670-4a55-991f-d99125d9550f (old id 974378)
date added to LUP
2008-01-07 11:45:18
date last changed
2017-10-29 03:33:07
@article{d0ddc32f-7670-4a55-991f-d99125d9550f,
  abstract     = {Protein microarrays is a technology with great promise for high-throughput proteomics. Designing high-performance protein microarrays for global proteome analysis has, however, turned out to be challenging. To this end, major efforts are under way to design novel array formats capable of harboring the tremendous range of probes required to target complex proteomes composed of more than 10 000 analytes. By adopting nanotechnology, the first generation of miniaturized nanoarrays has recently emerged, which opens up new avenues for global proteome analysis and disease proteomics. This review describes the progress and key issues in designing miniaturized protein arrays.},
  author       = {Borrebaeck, Carl and Wingren, Christer},
  issn         = {1878-5832},
  language     = {eng},
  number       = {19-20},
  pages        = {813--819},
  publisher    = {Elsevier},
  series       = {Drug Discovery Today},
  title        = {Progress in miniaturisation of proteon arrays - a step closer to high-density nanoarrays},
  url          = {http://dx.doi.org/10.1016/j.drudis.2007.08.003},
  volume       = {12},
  year         = {2007},
}