Simultaneous patch testing with fragrance markers in the baseline series and the ingredients of fragrance mixes : An update from southern Sweden
(2022) In Contact Dermatitis 86(6). p.514-523- Abstract
BACKGROUND: Regularly updating the prevalence of fragrance contact allergy (CA) is important. Patch testing with fragrance markers in the baseline series and the ingredients of fragrance mixes (FMs) is still debated.
OBJECTIVES: To update the prevalence and clinical characteristics of patients with fragrance CA. To establish the results of patch testing with individual allergens of FMs.
METHODS: A retrospective analysis of 3539 patients with dermatitis who were patch tested with the baseline series and FMs ingredients during 2016 to 2020 was performed.
RESULTS: The prevalence of fragrance CA was 13%. About 10% of these patients with fragrance CA would be missed if the individual ingredients were not tested. Unlike... (More)
BACKGROUND: Regularly updating the prevalence of fragrance contact allergy (CA) is important. Patch testing with fragrance markers in the baseline series and the ingredients of fragrance mixes (FMs) is still debated.
OBJECTIVES: To update the prevalence and clinical characteristics of patients with fragrance CA. To establish the results of patch testing with individual allergens of FMs.
METHODS: A retrospective analysis of 3539 patients with dermatitis who were patch tested with the baseline series and FMs ingredients during 2016 to 2020 was performed.
RESULTS: The prevalence of fragrance CA was 13%. About 10% of these patients with fragrance CA would be missed if the individual ingredients were not tested. Unlike hydroxyisohexyl 3-cyclohexene carboxaldehyde, there was no decreasing trend of CA to Evernia prunastri (oakmoss) extract after the EU regulation came into force. Patients with CA from only one ingredient of the mixes or having a weak positive reaction to the ingredients were significantly missed when tested with only the fragrance markers in the baseline series.
CONCLUSIONS: Patch testing with individual fragrance allergens is crucial for experts to expand knowledge in the fragrance CA field. The concentrations of the allergens in FMs may need to be adjusted to detect patients with fragrance CA, since some were significantly overlooked.
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- author
- Sukakul, Thanisorn LU ; Bruze, Magnus LU ; Mowitz, Martin LU ; Antelmi, Annarita LU ; Boonchai, Waranya ; Dahlin, Jakob LU ; Hamnerius, Nils LU ; Hauksson, Inese LU ; Lejding, Tina LU and Svedman, Cecilia LU
- organization
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Contact Dermatitis
- volume
- 86
- issue
- 6
- pages
- 514 - 523
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:35152428
- scopus:85125532621
- ISSN
- 0105-1873
- DOI
- 10.1111/cod.14072
- language
- English
- LU publication?
- yes
- additional info
- © 2022 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd.
- id
- 97c639c8-e14f-4619-9284-8b5923fb54c6
- date added to LUP
- 2022-04-12 14:11:12
- date last changed
- 2024-09-11 11:36:35
@article{97c639c8-e14f-4619-9284-8b5923fb54c6, abstract = {{<p>BACKGROUND: Regularly updating the prevalence of fragrance contact allergy (CA) is important. Patch testing with fragrance markers in the baseline series and the ingredients of fragrance mixes (FMs) is still debated.</p><p>OBJECTIVES: To update the prevalence and clinical characteristics of patients with fragrance CA. To establish the results of patch testing with individual allergens of FMs.</p><p>METHODS: A retrospective analysis of 3539 patients with dermatitis who were patch tested with the baseline series and FMs ingredients during 2016 to 2020 was performed.</p><p>RESULTS: The prevalence of fragrance CA was 13%. About 10% of these patients with fragrance CA would be missed if the individual ingredients were not tested. Unlike hydroxyisohexyl 3-cyclohexene carboxaldehyde, there was no decreasing trend of CA to Evernia prunastri (oakmoss) extract after the EU regulation came into force. Patients with CA from only one ingredient of the mixes or having a weak positive reaction to the ingredients were significantly missed when tested with only the fragrance markers in the baseline series.</p><p>CONCLUSIONS: Patch testing with individual fragrance allergens is crucial for experts to expand knowledge in the fragrance CA field. The concentrations of the allergens in FMs may need to be adjusted to detect patients with fragrance CA, since some were significantly overlooked.</p>}}, author = {{Sukakul, Thanisorn and Bruze, Magnus and Mowitz, Martin and Antelmi, Annarita and Boonchai, Waranya and Dahlin, Jakob and Hamnerius, Nils and Hauksson, Inese and Lejding, Tina and Svedman, Cecilia}}, issn = {{0105-1873}}, language = {{eng}}, number = {{6}}, pages = {{514--523}}, publisher = {{Wiley-Blackwell}}, series = {{Contact Dermatitis}}, title = {{Simultaneous patch testing with fragrance markers in the baseline series and the ingredients of fragrance mixes : An update from southern Sweden}}, url = {{http://dx.doi.org/10.1111/cod.14072}}, doi = {{10.1111/cod.14072}}, volume = {{86}}, year = {{2022}}, }