Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Recommendations for gonadotoxicity surveillance in male childhood, adolescent, and young adult cancer survivors : a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium

Skinner, Roderick ; Mulder, Renee L. ; Kremer, Leontien C. M. ; Hudson, Melissa M. ; Constine, Louis S. ; Bardi, Edit ; Boekhout, Annelies ; Borgmann-Staudt, Anja ; Brown, Morven C. and Cohn, Richard , et al. (2017) In The Lancet Oncology 18(2). p.75-90
Abstract

Treatment with chemotherapy, radiotherapy, or surgery that involves reproductive organs can cause impaired spermatogenesis, testosterone deficiency, and physical sexual dysfunction in male pubertal, adolescent, and young adult cancer survivors. Guidelines for surveillance and management of potential adverse effects could improve cancer survivors' health and quality of life. Surveillance recommendations vary considerably, causing uncertainty about optimum screening practices. This clinical practice guideline recommended by the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium, developed using evidence-based methodology, critically synthesises surveillance... (More)

Treatment with chemotherapy, radiotherapy, or surgery that involves reproductive organs can cause impaired spermatogenesis, testosterone deficiency, and physical sexual dysfunction in male pubertal, adolescent, and young adult cancer survivors. Guidelines for surveillance and management of potential adverse effects could improve cancer survivors' health and quality of life. Surveillance recommendations vary considerably, causing uncertainty about optimum screening practices. This clinical practice guideline recommended by the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium, developed using evidence-based methodology, critically synthesises surveillance recommendations for gonadotoxicity in male childhood, adolescent, and young adult (CAYA) cancer survivors. The recommendations were developed by an international multidisciplinary panel including 25 experts in relevant medical specialties, using a consistent and transparent process. Recommendations were graded according to the strength of underlying evidence and potential benefit gained by early detection and appropriate management. The aim of the recommendations is to enhance evidence-based care for male CAYA cancer survivors. The guidelines reveal the paucity of high-quality evidence, highlighting the need for further targeted research.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and , et al. (More)
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; and (Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
The Lancet Oncology
volume
18
issue
2
pages
75 - 90
publisher
Elsevier
external identifiers
  • scopus:85011933965
ISSN
1470-2045
DOI
10.1016/S1470-2045(17)30026-8
language
English
LU publication?
yes
id
98173fd1-d881-4d73-9e8d-0551e4732b43
date added to LUP
2017-02-28 09:44:59
date last changed
2022-05-02 17:59:05
@article{98173fd1-d881-4d73-9e8d-0551e4732b43,
  abstract     = {{<p>Treatment with chemotherapy, radiotherapy, or surgery that involves reproductive organs can cause impaired spermatogenesis, testosterone deficiency, and physical sexual dysfunction in male pubertal, adolescent, and young adult cancer survivors. Guidelines for surveillance and management of potential adverse effects could improve cancer survivors' health and quality of life. Surveillance recommendations vary considerably, causing uncertainty about optimum screening practices. This clinical practice guideline recommended by the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium, developed using evidence-based methodology, critically synthesises surveillance recommendations for gonadotoxicity in male childhood, adolescent, and young adult (CAYA) cancer survivors. The recommendations were developed by an international multidisciplinary panel including 25 experts in relevant medical specialties, using a consistent and transparent process. Recommendations were graded according to the strength of underlying evidence and potential benefit gained by early detection and appropriate management. The aim of the recommendations is to enhance evidence-based care for male CAYA cancer survivors. The guidelines reveal the paucity of high-quality evidence, highlighting the need for further targeted research.</p>}},
  author       = {{Skinner, Roderick and Mulder, Renee L. and Kremer, Leontien C. M. and Hudson, Melissa M. and Constine, Louis S. and Bardi, Edit and Boekhout, Annelies and Borgmann-Staudt, Anja and Brown, Morven C. and Cohn, Richard and Dirksen, Uta and Giwercman, Aleksander and Ishiguro, Hiroyuki and Jahnukainen, Kirsi and Kenney, Lisa B. and Loonen, Jacqueline J. and Meacham, Lilian and Neggers, Sebastian J. and Nussey, Stephen and Petersen, Cecilia and Shnorhavorian, Margarett and van den Heuvel-Eibrink, Marry M. and Van Santen, Hanneke M. and Wallace, William H B and Green, Daniel M.}},
  issn         = {{1470-2045}},
  language     = {{eng}},
  month        = {{02}},
  number       = {{2}},
  pages        = {{75--90}},
  publisher    = {{Elsevier}},
  series       = {{The Lancet Oncology}},
  title        = {{Recommendations for gonadotoxicity surveillance in male childhood, adolescent, and young adult cancer survivors : a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium}},
  url          = {{http://dx.doi.org/10.1016/S1470-2045(17)30026-8}},
  doi          = {{10.1016/S1470-2045(17)30026-8}},
  volume       = {{18}},
  year         = {{2017}},
}