Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Continuous glucose monitoring systems give contact dermatitis in children and adults despite efforts of providing less ‘allergy- prone’ devices : investigation and advice hampered by insufficient material for optimized patch test investigations

Svedman, C. LU ; Bruze, M. LU ; Antelmi, A. LU ; Hamnerius, N. LU ; Hauksson, I. LU ; Ulriksdotter, J. LU orcid and Mowitz, M. LU (2021) In Journal of the European Academy of Dermatology and Venereology 35(3). p.730-737
Abstract

Background: Medical devices are increasingly being reported to cause contact allergic dermatitis reactions. Objective: Review of patients with diabetes type I referred for suspected allergic contact dermatitis to insulin pump or glucose sensor systems. Method: We have reviewed 11 referred diabetes mellitus patients investigated for allergic contact dermatitis reactions to medical devices and specifically Dexcom G6®. Extracts from the medical devices were analysed. Results: The majority of patients was children, the majority had relevant allergies and particularly allergy to isobornyl acrylate which was also found in the glucose sensor system Dexcom G6®. Conclusions: The following case reports bring in focus the... (More)

Background: Medical devices are increasingly being reported to cause contact allergic dermatitis reactions. Objective: Review of patients with diabetes type I referred for suspected allergic contact dermatitis to insulin pump or glucose sensor systems. Method: We have reviewed 11 referred diabetes mellitus patients investigated for allergic contact dermatitis reactions to medical devices and specifically Dexcom G6®. Extracts from the medical devices were analysed. Results: The majority of patients was children, the majority had relevant allergies and particularly allergy to isobornyl acrylate which was also found in the glucose sensor system Dexcom G6®. Conclusions: The following case reports bring in focus the fact that patients sensitized through use of one medical device and being advised the use of another, or find another product for a while useful, are not by necessity free from future episodes of allergic contact dermatitis. The case reports emphasize the need for collaboration since it is impossible for even well-equipped laboratories to properly investigate the medical devices when information on the substances used in production is not uniform and complete and material to investigate are scarce. The importance of adequate patch test series and testing with own material and furthermore the importance to re-analyse medical devices and re-analyse test data are emphasized.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of the European Academy of Dermatology and Venereology
volume
35
issue
3
pages
8 pages
publisher
Elsevier
external identifiers
  • scopus:85101320615
  • pmid:33034101
ISSN
0926-9959
DOI
10.1111/jdv.16981
language
English
LU publication?
yes
id
988a4fae-4eee-4531-a65b-18a3ec53841e
date added to LUP
2021-03-09 10:22:05
date last changed
2024-06-13 08:07:43
@article{988a4fae-4eee-4531-a65b-18a3ec53841e,
  abstract     = {{<p>Background: Medical devices are increasingly being reported to cause contact allergic dermatitis reactions. Objective: Review of patients with diabetes type I referred for suspected allergic contact dermatitis to insulin pump or glucose sensor systems. Method: We have reviewed 11 referred diabetes mellitus patients investigated for allergic contact dermatitis reactions to medical devices and specifically Dexcom G6<sup>®</sup>. Extracts from the medical devices were analysed. Results: The majority of patients was children, the majority had relevant allergies and particularly allergy to isobornyl acrylate which was also found in the glucose sensor system Dexcom G6<sup>®</sup>. Conclusions: The following case reports bring in focus the fact that patients sensitized through use of one medical device and being advised the use of another, or find another product for a while useful, are not by necessity free from future episodes of allergic contact dermatitis. The case reports emphasize the need for collaboration since it is impossible for even well-equipped laboratories to properly investigate the medical devices when information on the substances used in production is not uniform and complete and material to investigate are scarce. The importance of adequate patch test series and testing with own material and furthermore the importance to re-analyse medical devices and re-analyse test data are emphasized.</p>}},
  author       = {{Svedman, C. and Bruze, M. and Antelmi, A. and Hamnerius, N. and Hauksson, I. and Ulriksdotter, J. and Mowitz, M.}},
  issn         = {{0926-9959}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{730--737}},
  publisher    = {{Elsevier}},
  series       = {{Journal of the European Academy of Dermatology and Venereology}},
  title        = {{Continuous glucose monitoring systems give contact dermatitis in children and adults despite efforts of providing less ‘allergy- prone’ devices : investigation and advice hampered by insufficient material for optimized patch test investigations}},
  url          = {{http://dx.doi.org/10.1111/jdv.16981}},
  doi          = {{10.1111/jdv.16981}},
  volume       = {{35}},
  year         = {{2021}},
}