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Revisiting the Glires concept—phylogenetic analysis of nuclear sequences

Misawa, K and Janke, Axel LU (2003) In Molecular Phylogenetics and Evolution 28(2). p.320-327
Abstract
The so-called Glires hypothesis postulates a sister-group relationship between Rodentia (e.g., rat and mouse) and Lagomorpha (e.g., rabbit). Recent molecular phylogenetic analyses have yielded incongruent results, and either supported or refuted the Glires grouping. In order to study this inconsistency we have reconstructed phylogenetic trees based on data sets of 20 orthologous nuclear protein coding genes (6441 aa, sites) and 12 mitochondrial protein coding genes (3559 aa sites). The size of the nuclear data set is considerably larger than any comparable data set hitherto used to study the Glires concept. Analysis of the nuclear data strongly supported the phylogenetic tree (frog, chicken, ((rat, mouse), (rabbit, (human, (cattle,... (More)
The so-called Glires hypothesis postulates a sister-group relationship between Rodentia (e.g., rat and mouse) and Lagomorpha (e.g., rabbit). Recent molecular phylogenetic analyses have yielded incongruent results, and either supported or refuted the Glires grouping. In order to study this inconsistency we have reconstructed phylogenetic trees based on data sets of 20 orthologous nuclear protein coding genes (6441 aa, sites) and 12 mitochondrial protein coding genes (3559 aa sites). The size of the nuclear data set is considerably larger than any comparable data set hitherto used to study the Glires concept. Analysis of the nuclear data strongly supported the phylogenetic tree (frog, chicken, ((rat, mouse), (rabbit, (human, (cattle, dog))))), while the mt data could not conclusively resolve the position of rabbit relative to that of human. This result was supported by all methods. Thus, the Glires hypothesis was rejected by this study. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Glires, Divergence times, Eutherian phylogeny, Nuclear proteins
in
Molecular Phylogenetics and Evolution
volume
28
issue
2
pages
320 - 327
publisher
Elsevier
external identifiers
  • scopus:0141832717
ISSN
1095-9513
DOI
10.1016/S1055-7903(03)00079-4
language
English
LU publication?
yes
id
fcbafa1d-f455-4566-8b07-0246877cc16f (old id 992244)
date added to LUP
2008-01-29 12:33:49
date last changed
2018-10-03 10:32:29
@article{fcbafa1d-f455-4566-8b07-0246877cc16f,
  abstract     = {The so-called Glires hypothesis postulates a sister-group relationship between Rodentia (e.g., rat and mouse) and Lagomorpha (e.g., rabbit). Recent molecular phylogenetic analyses have yielded incongruent results, and either supported or refuted the Glires grouping. In order to study this inconsistency we have reconstructed phylogenetic trees based on data sets of 20 orthologous nuclear protein coding genes (6441 aa, sites) and 12 mitochondrial protein coding genes (3559 aa sites). The size of the nuclear data set is considerably larger than any comparable data set hitherto used to study the Glires concept. Analysis of the nuclear data strongly supported the phylogenetic tree (frog, chicken, ((rat, mouse), (rabbit, (human, (cattle, dog))))), while the mt data could not conclusively resolve the position of rabbit relative to that of human. This result was supported by all methods. Thus, the Glires hypothesis was rejected by this study.},
  author       = {Misawa, K and Janke, Axel},
  issn         = {1095-9513},
  keyword      = {Glires,Divergence times,Eutherian phylogeny,Nuclear proteins},
  language     = {eng},
  number       = {2},
  pages        = {320--327},
  publisher    = {Elsevier},
  series       = {Molecular Phylogenetics and Evolution},
  title        = {Revisiting the Glires concept—phylogenetic analysis of nuclear sequences},
  url          = {http://dx.doi.org/10.1016/S1055-7903(03)00079-4},
  volume       = {28},
  year         = {2003},
}