Photoluminescent and tough hydrogels from silk fibroin and polyacrylic acid complexed with europium
(2024) In Journal of Applied Polymer Science- Abstract
Biocompatible, tough, and photoluminescent hydrogels are highly desirable for biomedical applications in vivo. Herein, hybrid hydrogels prepared from silk fibroin (SF) and polyacrylic acid (PAA) and complexed with europium, named as SF-PAA-Eu3+ hydrogels, exhibit good comprehensive properties. Owing to the intensive molecular interactions among SF, PAA, and Eu3+, SF-PAA-Eu3+ hydrogels show a greatest tensile strength of 0.58 MPa, elongation of 443%, and work of fracture of 1.65 MJ/m. In vivo imaging experiment in a mouse subcutaneous implantation model revealed excellent and sustained photoluminescence of the SF-PAA-Eu3+ hydrogels for 24 h. The work provides a strategy for designing functional... (More)
Biocompatible, tough, and photoluminescent hydrogels are highly desirable for biomedical applications in vivo. Herein, hybrid hydrogels prepared from silk fibroin (SF) and polyacrylic acid (PAA) and complexed with europium, named as SF-PAA-Eu3+ hydrogels, exhibit good comprehensive properties. Owing to the intensive molecular interactions among SF, PAA, and Eu3+, SF-PAA-Eu3+ hydrogels show a greatest tensile strength of 0.58 MPa, elongation of 443%, and work of fracture of 1.65 MJ/m. In vivo imaging experiment in a mouse subcutaneous implantation model revealed excellent and sustained photoluminescence of the SF-PAA-Eu3+ hydrogels for 24 h. The work provides a strategy for designing functional SF-based hydrogels for imaging applications in vivo.
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- author
- Zhao, Yu ; Puthia, Manoj LU ; Jo, Seong Min ; Guan, Juan ; Liu, Mingjie and Wu, Sujun
- organization
- publishing date
- 2024
- type
- Contribution to journal
- publication status
- epub
- subject
- keywords
- double network, europium, hydrogel, photoluminescence, silk fibroin
- in
- Journal of Applied Polymer Science
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- scopus:85182426027
- ISSN
- 0021-8995
- DOI
- 10.1002/app.55213
- language
- English
- LU publication?
- yes
- id
- 99ac25dc-ec40-495a-9b87-2fc62936fe7c
- date added to LUP
- 2024-02-16 13:22:04
- date last changed
- 2024-02-16 13:24:23
@article{99ac25dc-ec40-495a-9b87-2fc62936fe7c, abstract = {{<p>Biocompatible, tough, and photoluminescent hydrogels are highly desirable for biomedical applications in vivo. Herein, hybrid hydrogels prepared from silk fibroin (SF) and polyacrylic acid (PAA) and complexed with europium, named as SF-PAA-Eu<sup>3+</sup> hydrogels, exhibit good comprehensive properties. Owing to the intensive molecular interactions among SF, PAA, and Eu<sup>3+</sup>, SF-PAA-Eu<sup>3+</sup> hydrogels show a greatest tensile strength of 0.58 MPa, elongation of 443%, and work of fracture of 1.65 MJ/m. In vivo imaging experiment in a mouse subcutaneous implantation model revealed excellent and sustained photoluminescence of the SF-PAA-Eu<sup>3+</sup> hydrogels for 24 h. The work provides a strategy for designing functional SF-based hydrogels for imaging applications in vivo.</p>}}, author = {{Zhao, Yu and Puthia, Manoj and Jo, Seong Min and Guan, Juan and Liu, Mingjie and Wu, Sujun}}, issn = {{0021-8995}}, keywords = {{double network; europium; hydrogel; photoluminescence; silk fibroin}}, language = {{eng}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Journal of Applied Polymer Science}}, title = {{Photoluminescent and tough hydrogels from silk fibroin and polyacrylic acid complexed with europium}}, url = {{http://dx.doi.org/10.1002/app.55213}}, doi = {{10.1002/app.55213}}, year = {{2024}}, }