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Elective Testicular Biopsy at the End of Maintenance Treatment for Acute Lymphoblastic Leukemia. A Prospective Study

Békássy, A. N.; Kullendorff, C. M. and Arnbjörnsson, E. LU (1992) In European Journal of Pediatric Surgery 2(6). p.352-354
Abstract

Open testicular wedge biopsy has electively been performed prior to completion of maintenance therapy for acute lymphoblastic leukemia. 25 boys during 6 years were included in this prospective study. Three boys developed testicular enlargement while on maintenance therapy and biopsies confirmed testicular leukemia. The remaining 22 boys were biopsied at termination of maintenance therapy. Occult testicular relapse was revealed on histologic examination in only one boy with normal testicular size. During the follow-up period, one boy developed overt testicular relapse two months after negative biopsy. These results will not justify electively performed routine biopsy prior to termination of chemotherapy. Instead, careful and minute... (More)

Open testicular wedge biopsy has electively been performed prior to completion of maintenance therapy for acute lymphoblastic leukemia. 25 boys during 6 years were included in this prospective study. Three boys developed testicular enlargement while on maintenance therapy and biopsies confirmed testicular leukemia. The remaining 22 boys were biopsied at termination of maintenance therapy. Occult testicular relapse was revealed on histologic examination in only one boy with normal testicular size. During the follow-up period, one boy developed overt testicular relapse two months after negative biopsy. These results will not justify electively performed routine biopsy prior to termination of chemotherapy. Instead, careful and minute clinical examination of the testicles, estimating their size and consistence, should be performed regularly at short intervals.

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Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Acute lymphoblastic leukemia, Children, Extramedullary leukemia, Routine procedure, Testicular wedge biopsy
in
European Journal of Pediatric Surgery
volume
2
issue
6
pages
3 pages
publisher
Georg Thieme Verlag
external identifiers
  • scopus:0027054712
ISSN
0939-7248
DOI
10.1055/s-2008-1063477
language
English
LU publication?
no
id
99b4eb71-51f9-47a1-b9f7-d22a0fb574e4
date added to LUP
2018-11-09 10:00:35
date last changed
2019-01-06 14:14:16
@article{99b4eb71-51f9-47a1-b9f7-d22a0fb574e4,
  abstract     = {<p>Open testicular wedge biopsy has electively been performed prior to completion of maintenance therapy for acute lymphoblastic leukemia. 25 boys during 6 years were included in this prospective study. Three boys developed testicular enlargement while on maintenance therapy and biopsies confirmed testicular leukemia. The remaining 22 boys were biopsied at termination of maintenance therapy. Occult testicular relapse was revealed on histologic examination in only one boy with normal testicular size. During the follow-up period, one boy developed overt testicular relapse two months after negative biopsy. These results will not justify electively performed routine biopsy prior to termination of chemotherapy. Instead, careful and minute clinical examination of the testicles, estimating their size and consistence, should be performed regularly at short intervals.</p>},
  author       = {Békássy, A. N. and Kullendorff, C. M. and Arnbjörnsson, E.},
  issn         = {0939-7248},
  keyword      = {Acute lymphoblastic leukemia,Children,Extramedullary leukemia,Routine procedure,Testicular wedge biopsy},
  language     = {eng},
  month        = {01},
  number       = {6},
  pages        = {352--354},
  publisher    = {Georg Thieme Verlag},
  series       = {European Journal of Pediatric Surgery},
  title        = {Elective Testicular Biopsy at the End of Maintenance Treatment for Acute Lymphoblastic Leukemia. A Prospective Study},
  url          = {http://dx.doi.org/10.1055/s-2008-1063477},
  volume       = {2},
  year         = {1992},
}