Acoustophoresis in polymer-based microfluidic devices : Modeling and experimental validation
Lickert, Fabian ; Ohlin, Mathias ; Bruus, Henrik and Ohlsson, Pelle LU
(2021)
In Journal of the Acoustical Society of America
149(6).
p.4281-4291
- Abstract
A finite-element model is presented for numerical simulation in three dimensions of acoustophoresis of suspended microparticles in a microchannel embedded in a polymer chip and driven by an attached piezoelectric transducer at MHz frequencies. In accordance with the recently introduced principle of whole-system ultrasound resonances, an optimal resonance mode is identified that is related to an acoustic resonance of the combined transducer-chip-channel system and not to the conventional pressure half-wave resonance of the microchannel. The acoustophoretic action in the microchannel is of comparable quality and strength to conventional silicon-glass or pure glass devices. The numerical predictions are validated by acoustic focusing... (More)
A finite-element model is presented for numerical simulation in three dimensions of acoustophoresis of suspended microparticles in a microchannel embedded in a polymer chip and driven by an attached piezoelectric transducer at MHz frequencies. In accordance with the recently introduced principle of whole-system ultrasound resonances, an optimal resonance mode is identified that is related to an acoustic resonance of the combined transducer-chip-channel system and not to the conventional pressure half-wave resonance of the microchannel. The acoustophoretic action in the microchannel is of comparable quality and strength to conventional silicon-glass or pure glass devices. The numerical predictions are validated by acoustic focusing experiments on 5-μm-diameter polystyrene particles suspended inside a microchannel, which was milled into a polymethylmethacrylate chip. The system was driven anti-symmetrically by a piezoelectric transducer, driven by a 30-V peak-to-peak alternating voltage in the range from 0.5 to 2.5 MHz, leading to acoustic energy densities of 13 J/m3 and particle focusing times of 6.6 s.
(Less)
- author
- Lickert, Fabian
; Ohlin, Mathias
; Bruus, Henrik
and Ohlsson, Pelle
LU
- publishing date
- 2021-06-16
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of the Acoustical Society of America
- volume
- 149
- issue
- 6
- pages
- 11 pages
- publisher
- American Institute of Physics (AIP)
- external identifiers
-
- pmid:34241446
- scopus:85108086050
- ISSN
- 0001-4966
- DOI
- 10.1121/10.0005113
- language
- English
- LU publication?
- no
- additional info
- Funding Information: This work is part of the Eureka Eurostars-2 joint programme E!113461 AcouPlast project funded by Innovation Fund Denmark, Grant No. 9046-00127B, and Vinnova, Sweden’s Innovation Agency, Grant No. 2019–04500, with co-funding from the European Union Horizon 2020 Research and Innovation Programme. Publisher Copyright: © 2021 Acoustical Society of America. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
- id
- 9a1ec220-acde-40cc-b30d-ff5e8a77ee89
- date added to LUP
- 2021-07-06 15:50:30
- date last changed
- 2025-06-03 09:48:59
@article{9a1ec220-acde-40cc-b30d-ff5e8a77ee89,
abstract = {{<p>A finite-element model is presented for numerical simulation in three dimensions of acoustophoresis of suspended microparticles in a microchannel embedded in a polymer chip and driven by an attached piezoelectric transducer at MHz frequencies. In accordance with the recently introduced principle of whole-system ultrasound resonances, an optimal resonance mode is identified that is related to an acoustic resonance of the combined transducer-chip-channel system and not to the conventional pressure half-wave resonance of the microchannel. The acoustophoretic action in the microchannel is of comparable quality and strength to conventional silicon-glass or pure glass devices. The numerical predictions are validated by acoustic focusing experiments on 5-μm-diameter polystyrene particles suspended inside a microchannel, which was milled into a polymethylmethacrylate chip. The system was driven anti-symmetrically by a piezoelectric transducer, driven by a 30-V peak-to-peak alternating voltage in the range from 0.5 to 2.5 MHz, leading to acoustic energy densities of 13 J/m<sup>3</sup> and particle focusing times of 6.6 s.</p>}},
author = {{Lickert, Fabian and Ohlin, Mathias and Bruus, Henrik and Ohlsson, Pelle}},
issn = {{0001-4966}},
language = {{eng}},
month = {{06}},
number = {{6}},
pages = {{4281--4291}},
publisher = {{American Institute of Physics (AIP)}},
series = {{Journal of the Acoustical Society of America}},
title = {{Acoustophoresis in polymer-based microfluidic devices : Modeling and experimental validation}},
url = {{http://dx.doi.org/10.1121/10.0005113}},
doi = {{10.1121/10.0005113}},
volume = {{149}},
year = {{2021}},
}